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. 2020 Feb;61(1):e60-e64.
doi: 10.1111/ajd.13154. Epub 2019 Sep 10.

Body mass index and serum lipid profile: Association with atopic dermatitis in a paediatric population

Pedro Jesús Agón-Banzo  1 , Rosalía Sanmartin  2 , Ana Julia García-Malinis  3 , Ángela Hernández-Martín  4 , José Puzo  5 , Divina Doste  6 , Carlos Pardos  1 , Yolanda Gilaberte  7
Affiliations

Body mass index and serum lipid profile: Association with atopic dermatitis in a paediatric population

Pedro Jesús Agón-Banzo et al. Australas J Dermatol. 2020 Feb.

Abstract

Background/objectives: The association between atopic dermatitis, body weight and serum lipid levels is not well known, and very few studies have examined this relationship in children.

Methods: Children (n = 239) under 14 years old participated in this prospective cross-sectional study. The following variables were recorded: age, gender, weight, height, atopic dermatitis severity, serum levels of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides.

Results: Mean body mass index was slightly higher in atopic dermatitis patients than healthy controls and significantly higher in atopic dermatitis patients aged 0-2 years (atopic dermatitis, 16.7 ± 4.6; controls, 15.7 ± 1.3; P = 0.04) and 12-14 years (atopic dermatitis, 24.9 ± 5.3; controls, 20.6 ± 3.4; P = 0.03). Among atopic dermatitis patients, body mass index was significantly higher in those with severe atopic dermatitis in the 9-12 (P = 0.03) and 12-14 (P = 0.01) years groups. Mean serum lipid levels were higher in patients with severe atopic dermatitis than in the atopic dermatitis group as a whole. These differences reached statistical significance for total cholesterol (P = 0.04) and triglycerides (P = 0.02).

Conclusion: The prevalence of overweight, obesity and dyslipidemia is greater in children with atopic dermatitis than in age-matched healthy counterparts.

Keywords: atopic dermatitis; body mass index; dyslipidemia; metabolic syndrome; obesity; overweight.

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References

    1. Spergel JM. Epidemiology of atopic dermatitis and atopic march in children. Immunol. Allergy Clin. North Am. 2010; 30: 269-80.
    1. Thomsen SF. Atopic dermatitis: natural history, diagnosis, and treatment. ISRN Allergy 2014; 2014: 354250.
    1. Zhang A, Silverberg JI. Association of atopic dermatitis with being overweight and obese: a systematic review and metaanalysis. J. Am. Acad. Dermatol. 2015; 72: 606-16.e4.
    1. Sutherland ER. Linking obesity and asthma. Ann. N. Y. Acad. Sci. 2014; 1311: 31-41.
    1. Carrascosa A, Fernández JM, Fernández M et al. Estudios españoles de crecimiento 2010. Available from URL: tppp://www.aeped.es/noticias/estudios-espanoles-crecimiento-2010. (consultado 3 June 2016.)

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