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Review
. 2019 Jul 31;17(7):463-472.
doi: 10.18502/ijrm.v17i7.4857. eCollection 2019 Jul.

The relationship between body mass index and preeclampsia: A systematic review and meta-analysis

Morteza Motedayen  1 , Mohammad Rafiei  2 , Mostafa Rezaei Tavirani  3 , Kourosh Sayehmiri  4 , Majid Dousti  4
Affiliations
Review

The relationship between body mass index and preeclampsia: A systematic review and meta-analysis

Morteza Motedayen et al. Int J Reprod Biomed. .

Abstract

Background: One of the causes of maternal and fetal mortality and morbidity is pregnancy-induced hypertension, the most common form of which is preeclampsia that causes many complications for mother and fetus.

Objective: The aim of this systematic review and meta-analysis was to determine the relationship between body mass index (BMI) and preeclampsia in Iran.

Materials and methods: Using valid keywords in the SID database, PubMed, Scopus, data obtained from all the articles, which were reviewed in Iran between 2000 and 2016, were combined using the meta-analysis method (random-effects model) and analyzed using STATA version 11.1.

Results: A total number of 5,946 samples were enrolled in 16 studies with the mean BMI values of 25.13, 27.42, and 26.33 kg /m 2 in the healthy, mild, and severe preeclamptic groups, respectively.

Conclusion: The results of this study revealed that there is a significant relationship between BMI and the risk of preeclampsia, so it can be said that BMI may be one of the ways to diagnose preeclampsia.

Keywords: Body mass index; Iran; Meta-analysis.; Preeclampsia.

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Conflict of interest statement

The authors declare that there is no conflict of interest.

Figures

Figure 1
Figure 1
Flowchart of the stages of the systematic review and meta-analysis.
Figure 2
Figure 2
BMI in healthy pregnant women, by year, prevalence rate, and 95% CI interval. Each line segment shows the CI length. The diamond sign indicates the result of combining all studies at 95% CI.
Figure 3
Figure 3
The BMI value in pregnant women with mild PE, by year, prevalence rate, and 95% CI. Each line segment shows the CI length. The diamond sign indicates the result of combining all studies at 95% CI.
Figure 4
Figure 4
The BMI value in pregnant with severe PE, by year, prevalence rate, and 95% CI. Each line segment shows the CI length. The diamond sign indicates the result of combining all studies at 95% CI.
Figure 5
Figure 5
Beggs Funnel plot for publication bias.
See this image and copyright information in PMC

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