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Review
. 2019 Jul 31;17(7):463-472.
doi: 10.18502/ijrm.v17i7.4857. eCollection 2019 Jul.

The relationship between body mass index and preeclampsia: A systematic review and meta-analysis

Morteza Motedayen  1 , Mohammad Rafiei  2 , Mostafa Rezaei Tavirani  3 , Kourosh Sayehmiri  4 , Majid Dousti  4
Affiliations
Review

The relationship between body mass index and preeclampsia: A systematic review and meta-analysis

Morteza Motedayen et al. Int J Reprod Biomed. .

Abstract

Background: One of the causes of maternal and fetal mortality and morbidity is pregnancy-induced hypertension, the most common form of which is preeclampsia that causes many complications for mother and fetus.

Objective: The aim of this systematic review and meta-analysis was to determine the relationship between body mass index (BMI) and preeclampsia in Iran.

Materials and methods: Using valid keywords in the SID database, PubMed, Scopus, data obtained from all the articles, which were reviewed in Iran between 2000 and 2016, were combined using the meta-analysis method (random-effects model) and analyzed using STATA version 11.1.

Results: A total number of 5,946 samples were enrolled in 16 studies with the mean BMI values of 25.13, 27.42, and 26.33 kg /m 2 in the healthy, mild, and severe preeclamptic groups, respectively.

Conclusion: The results of this study revealed that there is a significant relationship between BMI and the risk of preeclampsia, so it can be said that BMI may be one of the ways to diagnose preeclampsia.

Keywords: Body mass index; Iran; Meta-analysis.; Preeclampsia.

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Conflict of interest statement

The authors declare that there is no conflict of interest.

Figures

Figure 1
Figure 1
Flowchart of the stages of the systematic review and meta-analysis.
Figure 2
Figure 2
BMI in healthy pregnant women, by year, prevalence rate, and 95% CI interval. Each line segment shows the CI length. The diamond sign indicates the result of combining all studies at 95% CI.
Figure 3
Figure 3
The BMI value in pregnant women with mild PE, by year, prevalence rate, and 95% CI. Each line segment shows the CI length. The diamond sign indicates the result of combining all studies at 95% CI.
Figure 4
Figure 4
The BMI value in pregnant with severe PE, by year, prevalence rate, and 95% CI. Each line segment shows the CI length. The diamond sign indicates the result of combining all studies at 95% CI.
Figure 5
Figure 5
Beggs Funnel plot for publication bias.
See this image and copyright information in PMC

References

    1. Cuningham F., Leveno K., Bloom S., Hauth J., Gilstrap L., Katharine W. Williams Obstetrics. 22th. New York: Mccraw-Hill; 2005. Williams obstetrics; p. 768.
    1. Ferrazzani S., Caruso A., De Carolis S., Martino I. V., Mancuso S. Proteinuria and outcome of 444 pregnancies complicated by hypertension. American Journal of Obstetrics & Gynecology. 1990;162(2):366–371. doi: 10.1016/0002-9378(90)90387-M. - DOI - PubMed
    1. Cunnigham FG., Gant NF., Leveno KJ., Larry C. Obstetrics. Journal of Midwifery Womens Health. 2010:48–369.
    1. Shah S., Gupta A. Gupta A. Hypertensive disorders of pregnancy. Cardiol Clin. Vol. 37. 37: 345-354; 2019. Hypertensive disorders of pregnancy. Cardiol Clin; pp. 345–354. - PubMed
    1. Broughton Pipkin F. Risk factors for preeclampsia: Editorial. The New England Journal of Medicine. 2001;344(12):925–926. doi: 10.1056/NEJM200103223441209. - DOI - PubMed

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