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. 1988;33(10):765-7.
doi: 10.1016/0003-9969(88)90011-8.

The status of sulphated isomers of glycosaminoglycans in fluorosed human teeth

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The status of sulphated isomers of glycosaminoglycans in fluorosed human teeth

A K Susheela et al. Arch Oral Biol. 1988.

Abstract

Fluorosed human teeth have lower concentrations of glycosaminoglycan (GAG) disaccharides and an increased dermatan sulphate content. Teeth from subjects with a high fluoride intake have a higher ratio of 4-sulphated to 6-sulphated GAGs. Increased dermatan sulphate may be an important factor in the clinical manifestations of fluorosis.

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