The status of sulphated isomers of glycosaminoglycans in fluorosed human teeth
- PMID: 3150922
- DOI: 10.1016/0003-9969(88)90011-8
The status of sulphated isomers of glycosaminoglycans in fluorosed human teeth
Abstract
Fluorosed human teeth have lower concentrations of glycosaminoglycan (GAG) disaccharides and an increased dermatan sulphate content. Teeth from subjects with a high fluoride intake have a higher ratio of 4-sulphated to 6-sulphated GAGs. Increased dermatan sulphate may be an important factor in the clinical manifestations of fluorosis.
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