Experimental Delineation of Mutational Signatures Is an Essential Tool in Cancer Epidemiology and Prevention
- PMID: 31509385
- DOI: 10.1021/acs.chemrestox.9b00339
Experimental Delineation of Mutational Signatures Is an Essential Tool in Cancer Epidemiology and Prevention
Abstract
Advances in experimental modeling of the mutational signatures of environmental exposures and endogenous mutagenic processes will elucidate the role of mutagenesis in cancer, facilitate carcinogen classification, and enable new molecular cancer epidemiology studies.
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