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. 2019 Sep 12;12(1):96.
doi: 10.1186/s13045-019-0783-9.

Incidence and death in 29 cancer groups in 2017 and trend analysis from 1990 to 2017 from the Global Burden of Disease Study

Longfei Lin  1 , Lei Yan  2 , Yuling Liu  1 , Fang Yuan  3 , Hui Li  4 , Jian Ni  5
Affiliations

Incidence and death in 29 cancer groups in 2017 and trend analysis from 1990 to 2017 from the Global Burden of Disease Study

Longfei Lin et al. J Hematol Oncol. .

Abstract

Background and aims: Cancer has become the second most serious disease threatening human health, followed by cardiovascular diseases. This study aimed to quantitatively estimate the mortality, morbidity, and analyze the trends of 29 cancer groups in 195 countries/regions between 1990 and 2017.

Methods: Detailed information of 29 cancer groups were collected from the Global Burden of Disease (GBD) study in 2017 and age-standardized incidence rates (ASIR) and age-standardized death rates (ASDR) of 29 cancer groups were calculated based on gender, age, region, and country. Trend analyses were conducted for major cancer types.

Results: In 2017, the global death population caused by cancer reached 9 million, which was nearly twice the number in 1990. The ASDR and ASIR of cancer in males were about 1.5 times those of females. Breast cancer showed the highest mortality rate in females in 2017. Individuals aged over 50 are at high risk of developing cancer and the number of cases and deaths in this age group accounted for more than 80% of all cancers in all age groups. Asia has the heaviest cancer burden due to its large population density. Different cancers in varied countries globally have their own characteristics. The ASDR and ASIR of some major cancers demonstrated changes from 1990 to 2017.

Conclusions: Analyses of these data provided basis for future investigations to the common etiological factors, leading to the occurrence of different cancers, the development of prevention strategies based on local characteristics, socioeconomic and other conditions, and the formulation of more targeted interventions.

Keywords: Cancer; Global burden of disease; Incidence and death; Trend analysis.

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Conflict of interest statement

All financial and non-financial competing interests must be declared in this section.

Figures

Fig. 1
Fig. 1
The age standardized global deaths and incidence of 29 specified cancer groups in 2017 by gender
Fig. 2
Fig. 2
Age-specific global contributions of cancer types to total cancer incidence in 2017
Fig. 3
Fig. 3
Cancers ranked by age-standardized deaths and incidence in 21 regions in 2017. a Age-standardized deaths per 100,000. b Age-standardized incidence per 100,000)
Fig. 4
Fig. 4
The age-standardized deaths and incidence of cancers in 21 regions compared with those globally in 2017. a Comparison of age-standardized deaths. b Comparison of age-standardized incidence
Fig. 5
Fig. 5
The age-standardized deaths and incidence (per 100,000) of 29 specified cancer groups in 2017 by different HDI regions
Fig. 6
Fig. 6
The global disease burden of cancers in 195 countries and territories. a ASDR of cancers in 2017. b ASIR of cancers in 2017
Fig. 7
Fig. 7
The relative changes in ASDR (a) and ASIR (b) of 29 specified cancer groups between 1990 and 2017
Fig. 8
Fig. 8
Twenty-nine specified cancers ranked by age-standardized deaths and incidence in 195 countries and territories in 2017. ASDR age-standardized deaths per 100,000, ASIR age-standardized incidence per 100,000
Fig. 9
Fig. 9
The relative changes in ASDR (a) and ASIR (b) of 29 specified cancer groups between 1990 and 2017 in 195 countries and territories. a Comparison of age-standardized deaths. b Comparison of age-standardized incidence
Fig. 10
Fig. 10
Trends in global breast cancer, ASDR (a), ASIR (b), death number (c), and incidence number (d) from 1990 to 2017
Fig. 11
Fig. 11
Trends in global prostate cancer, ASDR (a), ASIR (b), death number (c), and incidence number (d) from 1990 to 2017
Fig. 12
Fig. 12
Trends in global liver cancer, ASDR (a), ASIR (b), death number (c), and incidence number (d) from 1990 to 2017
Fig. 13
Fig. 13
Trends in global TBL cancer, ASDR (a), ASIR (b), death number (c), and incidence number (d) from 1990 to 2017
Fig. 14
Fig. 14
Trends in global colon and rectal cancer, ASDR (a), ASIR (b), death number (c), and incidence number (d) from 1990 to 2017
Fig. 15
Fig. 15
Trends in global gastric cancer, ASDR (a), ASIR (b), death number (c), and incidence number (d) from 1990 to 2017
See this image and copyright information in PMC

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