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Comment
. 2019 Oct 7;151(10):1159.
doi: 10.1085/jgp.201912479. Epub 2019 Sep 12.

Modeling GIRK channel conductance

Ben Short
Comment

Modeling GIRK channel conductance

Ben Short. J Gen Physiol. .

Abstract

JGP study uses MD simulations to investigate the gating and conductance of the inwardly rectifying potassium channel GIRK2.

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Figures

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Anna Stary-Weinzinger (left), Harald Bernsteiner (right), and colleagues use MD simulations to provide new details about the gating and conductance of the inwardly rectifying K+ channel GIRK2. The crystal structure of the channel bound to its activator, PIP2, shows the position of the HBC and G-loop gates, as well as five K+ ions (pink spheres) passing through the selectivity filter via what the simulations suggest is a direct knock-on mechanism.
See this image and copyright information in PMC

Comment on

References

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