Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019:130:76-87.

EXERCISE-ASSOCIATED HYPONATREMIA

Mitchell H Rosner  1
Affiliations

EXERCISE-ASSOCIATED HYPONATREMIA

Mitchell H Rosner. Trans Am Clin Climatol Assoc. 2019.

Abstract

Exercise-associated hyponatremia (EAH) is defined by an acute fall in the serum or plasma sodium concentration to below 135 mmol/L that occurs during or up to 24 hours after prolonged physical activity. EAH has been reported in nearly every form of endurance activity and has a common pathogenic feature of excessive water intake which is usually coupled with elevated vasopressin levels. Symptomatic EAH is uncommon but can be a cause of mortality in otherwise healthy adults and children. Rapid recognition and appropriate treatment with hypertonic saline are essential to maximizing outcomes and preventing death.

PubMed Disclaimer

Conflict of interest statement

Potential Conflicts of Interest: None disclosed.

References

    1. Noakes TD, Goodwin N, Rayner BL, et al. Water intoxication: a possible complication during endurance exercise. Med Sci Sports Exerc. 1985;17:370–5. - PubMed
    1. Montain SJ, Sawka MN, Wenger CB. Hyponatremia associated with exercise: risk factors and pathogenesis. Exerc Sport Sci Rev. 2001;29:113–7. - PubMed
    1. Speedy DB, Noakes TD, Schneider C. Exercise-associated hyponatremia: a review. Emerg Med (Fremantle) 2001;13:17–27. - PubMed
    1. Rosner MH, Kirven J. Exercise-associated hyponatremia. Clin J Am Soc Nephrol. 2007;2:151–61. - PubMed
    1. Rosner MH. Exercise-associated hyponatremia. Semin Nephrol. 2009;29:271–81. - PubMed