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Case Reports
. 2019 Jul 12;20(5):209-212.
doi: 10.1002/jgf2.269. eCollection 2019 Sep.

Asymptomatic ceftriaxone-associated pseudolithiasis

Osamu Sasaki  1 , Kazunori Sugimura  1 , Masahiro Shinoda  1 , Masaharu Shinkai  1
Affiliations
Case Reports

Asymptomatic ceftriaxone-associated pseudolithiasis

Osamu Sasaki et al. J Gen Fam Med. .

Abstract

An 88-year-old woman with a history of meningioma and dementia was admitted with high fever, loss of appetite, and nausea in July. Urinary tract infection was suspected. Computed tomography (CT) showed no significant findings. Urinary findings improved with administration of ceftriaxone. However, high fever appeared on hospital day 28, and CT identified a gallbladder stone without any abdominal symptoms. We considered the possibility of ceftriaxone-associated pseudolithiasis and changed pharmacotherapy to cefmetazole. CT on day 34 showed a reduction in the size of the gallbladder stone. Ceftriaxone-associated pseudolithiasis might arise in the absence of abdominal symptoms, and clinicians should take the patient background and season into account when using this agent.

Keywords: asymptomatic; ceftriaxone; high temperature; pseudolithiasis.

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1
A, Abdominal CT on admission shows no gallbladder stone. B, Abdominal CT on hospital day 28 (during ceftriaxone treatment) clearly shows a gallbladder stone (arrowhead). C, CT on hospital day 34 (after discontinuation of ceftriaxone) shows a reduction in size of the gallbladder stone
See this image and copyright information in PMC

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