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Case Reports
. 2019 Aug 14:28:100924.
doi: 10.1016/j.rmcr.2019.100924. eCollection 2019.

Spontaneous breathing during extracorporeal membrane oxygenation treatment of sickle cell disease acute chest syndrome

Thibaut Belveyre  1 , Thomas Auchet  1 , Bruno Levy  1   2
Affiliations
Case Reports

Spontaneous breathing during extracorporeal membrane oxygenation treatment of sickle cell disease acute chest syndrome

Thibaut Belveyre et al. Respir Med Case Rep. .

Abstract

Sickle cell disease (SCD) is a hereditary hemoglobinopathy resulting in sickling hemoglobin. Acute chest syndrome (ACS) is a serious complication of SCD and an important cause of morbidity and mortality. Management of ACS is complex and may necessitate mechanical ventilation and veno-venous extracorporeal membrane oxygenation (VV-ECMO) therapy in the more severe cases. We present herein the case of a young female adult (19 y.o.) with SCD who developed severe respiratory failure due to ACS occurring twice within 15 months and treated by VV-ECMO. We describe the management of ACS with VV-ECMO using two different approaches, namely with and without mechanical ventilation.

Keywords: Acute chest syndrome; Extracorporeal membrane oxygenation; Pulmonary hypertension; Sickle cell disease; Spontaneous breathing.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
Chest X-Ray on admission during the first ACS.
Fig. 2
Fig. 2
X-ray (left) and CT-scan (right) on admission during the second ACS.
See this image and copyright information in PMC

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