Infectious Adverse Events Following the Placement of a Penile Prosthesis: A Systematic Review
- PMID: 31519461
- DOI: 10.1016/j.sxmr.2019.07.005
Infectious Adverse Events Following the Placement of a Penile Prosthesis: A Systematic Review
Abstract
Introduction: Infection remains a prominent concern following penile implantation. Recognition of the risk factors for infection may help to guide surgeons toward reducing the risk of prosthetic contamination.
Aim: To gain a further understanding of infectious adverse events following penile prosthesis, we performed a systematic literature review.
Methods: As part of the 2018 American Urological Association Erectile Dysfunction Clinical Guidelines and with the support of the American Urological Association, we performed a comprehensive review of the PubMed, Embase, and Cochrane databases to search for eligible articles published between January 1, 1965, and July 20, 2016, to identify articles reporting infectious adverse events following prosthesis placement.
Main outcome measure: The main outcome measure was infectious adverse events following penile prosthesis placement.
Results: Ninety-one articles reporting infectious adverse events representing 97 study arms were identified. Prosthetic infection rates ranged from 0% to 24.6% across all series. Inflatable penile prostheses displayed a wider range (0-24.6%) than malleable devices (0-9.1%); the most frequently reported infection rate for inflatable devices was 5% or less. With the advent of device coatings and improved surgical techniques, infectious adverse events have decreased. Infections among diabetic patients also decreased throughout the reviewed body of literature, with the most recent series reporting rates consistent with those of non-diabetic patients. Furthermore, no glycosylated hemoglobin cutoff was found to infer increased or decreased risk of prosthesis infection.
Conclusion: Overall penile prosthetic infectious adverse events have decreased as surgical techniques have improved and the use of antimicrobial coating has gained in popularity. These advances have demonstrated significant benefits for all patients, particularly diabetic patients who experience infection rates similar to those of non-diabetic patients in recent reports. Further technological advancements for the prevention of biofilm formation is warranted. Mahon J, Dornbier R, Wegrzyn G, et al. Infectious Adverse Events Following the Placement of a Penile Prosthesis: A Systematic Review. Sex Med Rev 2020;8:348-354.
Keywords: Erectile Dysfunction; Infectious Adverse Event; Penile Prosthesis.
Copyright © 2019 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.
Comment in
-
Re: Infectious Adverse Events following the Placement of a Penile Prosthesis: A Systematic Review.J Urol. 2020 Feb;203(2):237. doi: 10.1097/01.JU.0000614832.09144.e8. Epub 2019 Nov 11. J Urol. 2020. PMID: 31710570 No abstract available.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Research Materials