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Meta-Analysis
. 2019 Sep 14;19(1):213.
doi: 10.1186/s12903-019-0903-5.

Prevalence of dental caries in children and adolescents with type 1 diabetes: a systematic review and meta-analysis

Yan Wang  1 , Lin Xing  2 , Hui Yu  1 , LiJuan Zhao  1
Affiliations
Meta-Analysis

Prevalence of dental caries in children and adolescents with type 1 diabetes: a systematic review and meta-analysis

Yan Wang et al. BMC Oral Health. .

Abstract

Background: Dental caries and type 1 diabetes are responsible for a large burden of global disease; however, the exact prevalence of dental caries among children and adolescents with type 1 diabetes remains controversial, and no quantitative meta-analysis exists. Thus, we performed a meta-analysis to evaluate the prevalence of dental caries among children and adolescents with type 1 diabetes.

Methods: We performed a systematic search strategy using PubMed, EMBASE and China National Knowledge Infrastructure for relevant studies investigating the prevalence of dental caries in children and adolescents with type 1 diabetes from July 1971 until December 2018. The pooled prevalence with 95% confidence intervals (95%CIs) and subgroup analyses were calculated using a random effects model.

Results: After screening 358 non-duplicated articles, a total of 10 articles involving 538 individuals were included. The overall prevalence of dental caries among children and adolescents with type 1 diabetes was 67% (95% CI: 0.56-0.77%; I2 = 83%). The prevalence was highest in South America (84%) and lowest in diabetic patients with good metabolic control (47%).

Conclusions: The prevalence of dental caries was high among children and adolescents with type 1 diabetes. Screening and preventive treatment should be included in dental clinical routines for diabetic children and adolescents, especially in those with poor metabolic control.

Keywords: Adolescent; Caries; Children; Diabetes; Meta-analysis; Prevalence.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Flow diagram of the literature search
Fig. 2
Fig. 2
Pooled prevalence of dental caries in children and adolescents with type 1 diabetes
Fig. 3
Fig. 3
Pooled prevalence of dental caries in children and adolescents with type 1 diabetes according to geographical region
Fig. 4
Fig. 4
Pooled prevalence of dental caries in children and adolescents with type 1 diabetes according to metabolic control
Fig. 5
Fig. 5
Pooled prevalence of dental caries in children and adolescents with type 1 diabetes according to mean age
Fig. 6
Fig. 6
One-study removed sensitivity analysis
Fig. 7
Fig. 7
Funnel plot for all studies
See this image and copyright information in PMC

Comment in

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