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. 2019 Jan 31;21(1):4-10.

Using a Composite Graft of Natural 15% Chitosan Gel in the Management of Intrabony Defects: A Case Series

Irfana Babrawala  1 , M L Prabhuji  2 , B V Karthikeyan  1
Affiliations
  • PMID: 31522157

Using a Composite Graft of Natural 15% Chitosan Gel in the Management of Intrabony Defects: A Case Series

Irfana Babrawala et al. J Int Acad Periodontol. .

Abstract

Introduction: The purpose of this study was to compare effects of smoking and smokeless forms of tobacco consumption (tobacco chewing) on periodontal disease parameters and response of these subjects to non-surgical periodontal therapy.

Materials and methods: Ten patients aged between 30 and 55 years with intrabony defects greater than or equal to 3 mm and pocket probing depth (PPD) greater than or equal to 5 mm were selected. All participants received chitosan gel (15% w/v) plus bovine porous bone mineral as a composite bone graft. Clinical and radiographic measurements were recorded at baseline, 3 months after healing and at 6 and 9 months. Significance was set at 0.05.

Results: After nine months, all the defects treated with this combination showed PPD reduction of 5.30 ± 0.822 mm, relative clinical attachment level (CAL) gain of 5.80 ± 0.499 mm, reduction in intrabony defect (IBD) depth of 3.00 ± 0.497 mm and defect resolution of 78.32 ± 5.80 %, all of which were statistically significant.

Conclusion: Within the limits of this study, this case series study suggests that chitosan gel, along with bovine porous bone mineral, has a promising role to play in periodontal regeneration.

Keywords: bovine porous bone material; chitosan; periodontal regeneration; wound healing.

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