Oncologic and functional outcomes of transoral CO2 laser cordectomy for early glottic cancer
- PMID: 31522907
- DOI: 10.1016/j.anl.2019.08.005
Oncologic and functional outcomes of transoral CO2 laser cordectomy for early glottic cancer
Abstract
Objective: To investigate the oncological and functional outcomes of the patients treated with transoral CO2 laser cordectomy for early glottic cancer.
Patients and methods: Fifty-five consecutive patients who underwent CO2 laser cordectomy for early glottic cancer were retrospectively reviewed.
Results: Overall survival, larynx preservation, and relapse free local control rates were 96%, 100%, and 91%, respectively. Five patients with local recurrences were salvaged with re-cordectomy and/or radiotherapy. In type I cordectomy, VHI-10 consistently improved during postoperative course and VHI-10 at postoperative 12months was significantly better than preoperative value (2.3 vs. 9.4, p=0.02). Perceptual grading, MPT, MFR and AC/DC also improved and were better than preoperative values. In type III cordectomy, shimmer at 12months after cordectomy was significantly better than preoperative value (14.7 vs. 9.3, p=0.007).
Conclusions: These results further support the rationale of CO2 cordectomy as initial and salvage surgery for early glottic cancer.
Keywords: Early glottic cancer; Transoral CO2 laser cordectomy.
Copyright © 2019. Published by Elsevier B.V.
Similar articles
-
Oncological and functional results of CO2 laser cordectomy.Acta Otorhinolaryngol Ital. 2004 Oct;24(5):267-74. Acta Otorhinolaryngol Ital. 2004. PMID: 15871607
-
CO2 laser cordectomy for glottic squamous cell carcinoma involving the anterior commissure: voice and oncologic outcomes.Eur Arch Otorhinolaryngol. 2015 Feb;272(2):413-8. doi: 10.1007/s00405-014-3368-9. Epub 2014 Oct 29. Eur Arch Otorhinolaryngol. 2015. PMID: 25351502
-
Vocal Outcome After Cordectomy by Transoral CO2 Laser Microsurgery in Patients With Laryngeal Intraepithelial Neoplasia and Non-neoplastic Lesions.J Voice. 2024 Nov;38(6):1533.e11-1533.e23. doi: 10.1016/j.jvoice.2022.04.018. Epub 2022 Jun 19. J Voice. 2024. PMID: 35732537
-
Voice Outcome After Carbon Dioxide Transoral Laser Microsurgery for Glottic Cancer According to the European Laryngological Society Classification of Cordectomy Types - A Systematic Review.J Voice. 2024 Sep;38(5):1227-1236. doi: 10.1016/j.jvoice.2022.03.003. Epub 2022 Apr 12. J Voice. 2024. PMID: 35422356
-
Reconstruction of glottic defects after endoscopic cordectomy: voice outcome.Otolaryngol Clin North Am. 2006 Feb;39(1):191-204. doi: 10.1016/j.otc.2005.10.010. Otolaryngol Clin North Am. 2006. PMID: 16469663 Review. No abstract available.
Cited by
-
Voice quality after transoral CO2 laser microsurgery (TOLMS): systematic review of literature.Eur Arch Otorhinolaryngol. 2022 Sep;279(9):4247-4255. doi: 10.1007/s00405-022-07418-3. Epub 2022 May 3. Eur Arch Otorhinolaryngol. 2022. PMID: 35505113 Free PMC article.
-
Impact of resection margin status and revision transoral laser microsurgery in early glottic cancer: analysis of organ preservation and local disease control on a cohort of 153 patients.Braz J Otorhinolaryngol. 2022 Sep-Oct;88(5):669-674. doi: 10.1016/j.bjorl.2020.09.008. Epub 2020 Oct 17. Braz J Otorhinolaryngol. 2022. PMID: 33272837 Free PMC article.
-
Oncological and Functional Outcomes After Type III Cordectomy for Early Glottic Cancer (Tis, T1a): A Retrospective Study Based on Our 10-Year Experience.J Clin Med. 2024 Nov 26;13(23):7164. doi: 10.3390/jcm13237164. J Clin Med. 2024. PMID: 39685623 Free PMC article.
-
Prognosis and Outcomes in Early Stage Glottic Carcinoma Involving the Anterior Commissure Treated with Laser CO2 Surgery: A Retrospective Observational Analysis.Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):6048-6053. doi: 10.1007/s12070-021-02698-3. Epub 2021 Jun 27. Indian J Otolaryngol Head Neck Surg. 2022. PMID: 36742721 Free PMC article.
-
Management of Early Glottic Cancer Treated by CO2 Laser According to Surgical-Margin Status: A Systematic Review of the Literature.Int Arch Otorhinolaryngol. 2021 Apr;25(2):e301-e308. doi: 10.1055/s-0040-1713922. Epub 2020 Sep 24. Int Arch Otorhinolaryngol. 2021. PMID: 33968237 Free PMC article. Review.
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous
