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Review
. 2019 Aug 15;11(4):105-114.
eCollection 2019.

Mechanism and adverse effects of multiple sclerosis drugs: a review article. Part 2

Aryan Rafiee Zadeh  1 , Keyvan Ghadimi  1 , Akram Ataei  2 , Mozhde Askari  1 , Neda Sheikhinia  2 , Nooshin Tavoosi  3 , Masih Falahatian  1
Affiliations
Review

Mechanism and adverse effects of multiple sclerosis drugs: a review article. Part 2

Aryan Rafiee Zadeh et al. Int J Physiol Pathophysiol Pharmacol. .

Abstract

Multiple Sclerosis (MS) is an autoimmune, inflammatory disease of the central nervous system (CNS) mostly affecting young adults. The exact mechanism and pathogenesis of MS remain still undiscovered but there have been useful treatments with different efficacy rates. Most of these therapies are divided into the first line, second line and third line, impact on the immune system and immune cells. These drugs are approved to be useful in MS, but like any other therapies, adverse effects (AE) are associated with these drugs. In this review, we continue the survey over mechanisms of actions and AEs of MS drugs. Physicians must be aware of such AEs and complications to choose the best drug for each patient.

Keywords: Mechanism; adverse effect; drug; multiple sclerosis.

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Conflict of interest statement

None.

References

    1. Farrokhi M, Beni AA, Etemadifar M, Rezaei A, Rivard L, Zadeh AR, Sedaghat N, Ghadimi M. Effect of fingolimod on platelet count among multiple sclerosis patients. Int J Prev Med. 2015;6:125. - PMC - PubMed
    1. Zadeh AR, Farrokhi M, Etemadifar M, Beni AA. Prevalence of benign tumors among patients with multiple sclerosis. American Journal of Experimental and Clinical Research. 2015;2:127–132.
    1. Trapp BD, Nave KA. Multiple sclerosis: an immune or neurodegenerative disorder? Annu Rev Neurosci. 2008;31:247–269. - PubMed
    1. Payghani C, Khani F, Zadeh AR, Reisi P, Alaei H, Rashidi B. The effect of levothyroxine on serum levels of interleukin 10 and interferon-gamma in rat model of multiple sclerosis. Adv Biomed Res. 2017;6:118. - PMC - PubMed
    1. Rafiee Zadeh A, Ghadimi K, Mohammadi B, Naghibi S, Danaeiniya A. Effects of estrogen and progesterone on differ-ent immune cells related to multiple sclerosis. Caspian J Neurol Sci. 2018;4:39–46.

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