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Review
. 2019 Aug;12(8):e006213.
doi: 10.1161/CIRCHEARTFAILURE.119.006213. Epub 2019 Aug 1.

Heart Rate and Heart Failure With Preserved Ejection Fraction: Time to Slow β-Blocker Use?

Markus Meyer  1 , Martin M LeWinter  1
Affiliations
Review

Heart Rate and Heart Failure With Preserved Ejection Fraction: Time to Slow β-Blocker Use?

Markus Meyer et al. Circ Heart Fail. 2019 Aug.
No abstract available

Keywords: atrial fibrillation; beta blockers; heart failure; heart rate; hypertension.

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Figures

Figure 1.
Figure 1.
Illustration of the acute effects of an increase in heart rate in HFpEF.
See this image and copyright information in PMC

References

    1. Topol EJ, Traill TA, Fortuin NJ. Hypertensive hypertrophic cardiomyopathy of the elderly. N Engl J Med. 1985;312:277–83. - PubMed
    1. Solomon SD, Rizkala AR, Lefkowitz MP, Shi VC, Gong J, Anavekar N, Anker SD, Arango JL, Arenas JL, Atar D, Ben-Gal T, Boytsov SA, Chen CH, Chopra VK, Cleland J, Comin-Colet J, Duengen HD, Echeverría Correa LE, Filippatos G, Flammer AJ, Galinier M, Godoy A, Goncalvesova E, Janssens S, Katova T, Køber L, Lelonek M, Linssen G, Lund LH, O’Meara E, Merkely B, Milicic D, Oh BH, Perrone SV, Ranjith N, Saito Y, Saraiva JF, Shah S, Seferovic PM, Senni M, Sibulo AS Jr, Sim D, Sweitzer NK, Taurio J, Vinereanu D, Vrtovec B, Widimský J Jr, Yilmaz MB, Zhou J, Zweiker R, Anand IS, Ge J, Lam CSP, Maggioni AP, Martinez F, Packer M, Pfeffer MA, Pieske B, Redfield MM, Rouleau JL, Van Veldhuisen DJ, Zannad F, Zile MR, McMurray JJV. Baseline characteristics of patients with heart failure and preserved ejection fraction in the PARAGON-HF trial. Circ Heart Fail. 2018;11:e004962. doi: 10.1161/CIRCHEARTFAILURE.118.004962. - DOI - PubMed
    1. Snipelisky D, Kelly J, Levine JA, Koepp GA, Anstrom KJ, McNulty SE, Zakeri R, Felker GM, Hernandez AF, Braunwald E, Redfield MM. Accelerometer-measured daily activity in heart failure with preserved ejection fraction: Clinical correlates and association with standard heart failure severity indices. Circ Heart Fail. 2017;10:e003878. doi: 10.1161/CIRCHEARTFAILURE.117.003878. - DOI - PMC - PubMed
    1. Pieske B, Kretschmann B, Meyer M, Holubarsch C, Weirich J, Posival H, Minami K, Just H, Hasenfuss G. Alterations in intracellular calcium handling associated with the inverse force-frequency relation in human dilated cardiomyopathy. Circulation. 1995;92:1169–78. - PubMed
    1. Runte KE, Bell SP, Selby DE, Häußler TN, Ashikaga T, LeWinter MM, Palmer BM, Meyer M. Relaxation and the role of calcium in isolated contracting myocardium from patients with hypertensive heart disease and heart failure with preserved ejection fraction. Circ Heart Fail. 2017;10 pii: e004311. doi: 10.1161/CIRCHEARTFAILURE.117.004311. - DOI - PMC - PubMed

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