Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Sep-Oct;10(5):917-921.
doi: 10.1016/j.jcot.2019.02.016. Epub 2019 Feb 27.

Acute venous thromboembolism in Indian patients of isolated proximal femur fractures

Affiliations

Acute venous thromboembolism in Indian patients of isolated proximal femur fractures

Rahul Saket et al. J Clin Orthop Trauma. 2019 Sep-Oct.

Abstract

Introduction: Venous Thromboembolism (VTE) has a variable incidence in trauma patients and fatal embolism can be the very first manifestation. Proximal femur fractures result from high velocity trauma in younger age groups and could require prolonged immobilisation, which is associated with increased risk of VTE. Therefore we sought to determine the occurrance of VTE in patients with proximal femur fractures.

Objectives: The present study was initiated to assess the occurrance of deep vein thrombosis (DVT) or pulmonary embolism in isolated proximal femur fractures and identify the requirement of routine thromboprophylaxis in such patients.

Methods: It was a prospective study conducted over a period of one and a half years. All patients, presenting with isolated proximal femur fractures were included. Patients having any other known risk factors for DVT were excluded, so that the proximal femur fracture remained their only acquired risk for DVT. All the patients were evaluated clinically and with help of diagnostic modalities like Color Doppler with compression ultrasound, D-dimer assays and CT venogram, if indicated. Patients were followed up till 8 weeks post-operatively.

Results: A total of 66 patients with fractures of proximal femur were assessed, out of which there were 42 males with mean age of 48.1 years and 24 females with mean age of 58.3 years. A total of 9 cases of radiologically proved DVT were observed. Clinical DVT was seen in 5 of these cases (54%). Complete resolution of thrombus was noted in all the patients, evaluated by Color Doppler at 6 weeks, post diagnosis. Although the majority of the cases (6) occurred in patients beyond 50 years of age, this was not statistically significant.

Conclusion: DVT is common in patients with proximal femur fractures and the provision for screening both clinically and radiologically, should be made routine in all such patients. In case of delay in surgery and patient being bed ridden, we recommend thromboprophylaxis in this subset of trauma patients.

Keywords: DVT; Deep vein thrombosis; PE; Proximal femur fractures; Pulmonary Embolism; Thromboprophylaxis; VTE; Venous thromboembolism.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Geerts W.H., Code K.I., Jay R.M., Chen E., Szalai J.P. A prospective study of venous thromboembolism after major trauma. N Engl J Med. 1994 Dec 15;331(24):1601–1606. - PubMed
    1. Montgomery K.D., Geerts W.H., Potter H.G., Helfet D.L. Thromboembolic complications in patients with pelvic trauma. Clin Orthop Relat Res. 1996 Aug;(329):68–87. - PubMed
    1. Napolitano L.M., Garlapati V.S., Heard S.O. Asymptomatic deep venous thrombosis in the trauma patient: is an aggressive screening protocol justified? J Trauma. 1995 Oct;39(4):651–657. discussion 657-9. - PubMed
    1. Knudson M.M., Collins J.A., Goodman S.B., McCrory D.W. Thromboembolism following multiple trauma. J Trauma. 1992 Jan;32(1):2–11. - PubMed
    1. Geerts W.H., Bergqvist D., Pineo G.F. Prevention of venous thromboembolism: American college of chest physicians evidence-based clinical practice guidelines (8th edition) Chest. 2008 Jun;133(6 Suppl):381S–453S. - PubMed