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. 1979 Aug;37(2):190-5.

Occurrence of antibodies to single-stranded DNA in ANA negative patients

C A Wasicek, P J Maddison, M Reichlin

Occurrence of antibodies to single-stranded DNA in ANA negative patients

C A Wasicek et al. Clin Exp Immunol. 1979 Aug.

Abstract

Five patients with clinical features of a connective tissue disease most suggestive of systemic lupus erythematosus were found to have a negative ANA by conventional screening at 1/20 dilution on mouse liver. However, significant titres of antibodies to single-stranded DNA were detected using a double antibody radioimmunoassay. Thus, certain patients have antibodies to DNA restricted to single-stranded determinants as detected by radioimmunoassay with single-stranded DNA as antigen and a negative ANA test.

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References

    1. Arthritis Rheum. 1977 Sep-Oct;20(7):1320-5 - PubMed
    1. Arthritis Rheum. 1977 Nov-Dec;20(8):1457-63 - PubMed
    1. J Exp Med. 1967 Jan 1;125(1):61-70 - PubMed
    1. Ann N Y Acad Sci. 1975 Jun 30;254:505-15 - PubMed
    1. Arthritis Rheum. 1974 Jul-Aug;17(4):421-9 - PubMed

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