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Meta-Analysis
. 2020 Jan;127(1):8-16.
doi: 10.1111/1471-0528.15946. Epub 2019 Oct 24.

Prevalence and outcomes of prenatal recreational cannabis use in high-income countries: a scoping review

S Singh  1 , K B Filion  1   2   3 , H A Abenhaim  1   4 , M J Eisenberg  1   3   5
Affiliations
Meta-Analysis

Prevalence and outcomes of prenatal recreational cannabis use in high-income countries: a scoping review

S Singh et al. BJOG. 2020 Jan.

Abstract

Background: With expanding recreational cannabis legalisation, pregnant women and their offspring are at risk of potentially harmful consequences.

Objectives: To assess the prevalence of recreational cannabis use among pregnant women, health outcomes associated with prenatal recreational cannabis use, and the potential impact of recreational cannabis legalisation on this population.

Search strategy: Five databases and the grey literature were systematically searched (2000-2019).

Selection criteria: Human studies published in English or French reporting on the prevalence of prenatal recreational cannabis use in high-income countries.

Data collection and analysis: Data on study characteristics, prenatal substance use, and health outcomes were extracted and qualitatively synthesised.

Main results: Forty-one publications met our inclusion criteria. The overall prevalence of prenatal cannabis use varied substantially (min-max: 0.24-22.6%), with the greatest use in the first trimester. In the three studies with temporal data available, rates of prenatal cannabis use increased across years. Only 7/41 and 5/41 studies provided information on gestational age of exposure and frequency of use, respectively. The concomitant use of alcohol, illicit drugs, and tobacco was higher among cannabis users than nonusers. Prenatal cannabis use was associated with select neonatal, but not maternal, health outcomes. There were insufficient data to compare prenatal cannabis use between the pre- and post-legalisation periods.

Conclusion: Cannabis use among pregnant women is prevalent and may be associated with adverse neonatal outcomes. Future studies should assess the gestational age and frequency of cannabis exposure, and usage patterns prior to and following legalisation.

Tweetable abstract: Women who consume cannabis during pregnancy could risk predisposing their newborns to poor birth outcomes.

Keywords: Cannabis; maternal health; neonatal health; pregnancy; scoping review.

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References

    1. Metz TD, Stickrath EH. Marijuana use in pregnancy and lactation: a review of the evidence. Am J Obstet Gynecol 2015;213:761-78.
    1. Gunn JK, Rosales CB, Center KE, Nunez A, Gibson SJ, Christ C, et al. Prenatal exposure to cannabis and maternal and child health outcomes: a systematic review and meta-analysis. BMJ Open 2016;6:e009986.
    1. Conner SN, Bedell V, Lipsey K, Macones GA, Cahill AG, Tuuli MG. Maternal marijuana use and adverse neonatal outcomes: a systematic review and meta-analysis. Obstet Gynecol 2016;128:713-23.
    1. ElSohly MA, Mehmedic Z, Foster S, Gon C, Chandra S, Church JC. Changes in cannabis potency over the last two decades (1995-2014) - analysis of current data in the United States. Biol Psychiatry 2016;79:613-9.
    1. Tricco AC, Lillie E, Zarin W, O'Brien KK, Colquhoun H, Levac D, et al. PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Ann Intern Med 2018;169:467-73.

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