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. 1988 Jul;2(3):288-90.
doi: 10.1007/BF00858679.

Haemolytic uraemic syndrome associated with faecal cytotoxin and verotoxin neutralizing antibodies

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Haemolytic uraemic syndrome associated with faecal cytotoxin and verotoxin neutralizing antibodies

A A Novillo et al. Pediatr Nephrol. 1988 Jul.

Abstract

Forty-nine patients with a diagnosis of idiopathic haemolytic uraemic syndrome (HUS) were investigated to determine evidence of infection by verotoxin-producing Escherichia coli (VTEC). Free faecal cytotoxin active on Vero cells (VT) was detected in 15 out of 49 patients (31%). Seroconversion or high titres of VT-neutralizing antibodies were detected in 11 out of 18 patients (61%). The results of the present study suggest an association between HUS and infection by VTEC.

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