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. 2019 Dec;30(12):1277-1282.
doi: 10.1007/s10552-019-01232-9. Epub 2019 Sep 17.

Racial disparities of liver cancer mortality in Wisconsin

Amin Bemanian  1   2 , Laura D Cassidy  3 , Raphael Fraser  3 , Purushottam W Laud  3 , Kia Saeian  4 , Kirsten M M Beyer  3
Affiliations

Racial disparities of liver cancer mortality in Wisconsin

Amin Bemanian et al. Cancer Causes Control. 2019 Dec.

Abstract

Purpose: To calculate tract-level estimates of liver cancer mortality in Wisconsin and identify relationships with racial and socioeconomic variables.

Methods: County-level standardized mortality ratios (SMRs) of liver cancer in Wisconsin were calculated using traditional indirect adjustment methods for cases from 2003 to 2012. Tract-level SMRs were calculated using adaptive spatial filtering (ASF). The tract-level SMRs were checked for correlations to a socioeconomic advantage index (SEA) and percent racial composition. Non-spatial and spatial regression analyses with tract-level SMR as the outcome were conducted.

Results: County-level SMR estimates were shown to mask much of the variance within counties across their tracts. Liver cancer mortality was strongly correlated with the percent of Black residents in a census tract and moderately associated with SEA. In the multivariate spatially-adjusted regression analysis, only Percent Black composition remained significantly associated with an increased liver cancer SMR.

Conclusions: Using ASF, we developed a high-resolution map of liver cancer mortality in Wisconsin. This map provided details on the distribution of liver cancer that were inaccessible in the county-level map. These tract-level estimates were associated with several racial and socioeconomic variables.

Keywords: Cancer epidemiology; Cancer mapping; Disparities; Liver cancer; Race.

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Figures

Figure 1
Figure 1
(TractMortalitySES.jpg): Maps of liver cancer mortality and covariates in Wisconsin. Black borders represent American Indian reservations and lands. Upper Left: Liver Cancer Standardized Mortality Ratio, Upper Right: Socioeconomic Advantage (NA values either due to no residents or survey standard error is too large), Center Left: Tract Rurality, Center Right: Percent Black/African American Residents, Bottom Left: Percent American Indian/Alaska Native Residents, Bottom Right: Percent Hispanic Residents
See this image and copyright information in PMC

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