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Comment
. 2019 Sep 17;51(3):426-428.
doi: 10.1016/j.immuni.2019.08.014.

Spicy Immunity: Pain to Gain

Nathachit Limjunyawong  1 , Xinzhong Dong  2
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Comment

Spicy Immunity: Pain to Gain

Nathachit Limjunyawong et al. Immunity. .
Free article

Abstract

The skin is densely innervated with nociceptive neurons specialized in detecting noxious and painful stimuli. In a recent issue of Cell, Cohen et al. report that activation of cutaneous nociceptive neurons leads to a nerve-reflex action that is sufficient to provide a danger signal that triggers regional immunity to fight a microbial challenge.

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