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Randomized Controlled Trial
. 2020 Aug 24;22(9):1587-1595.
doi: 10.1093/ntr/ntz176.

Exercise for Smoking Cessation in Postmenopausal Women: A Randomized, Controlled Trial

Cheryl Oncken  1 , Sharon Allen  2 , Mark Litt  3 , Anne Kenny  1 , Harry Lando  4 , Alicia Allen  5 , Ellen Dornelas  1   6
Affiliations
Randomized Controlled Trial

Exercise for Smoking Cessation in Postmenopausal Women: A Randomized, Controlled Trial

Cheryl Oncken et al. Nicotine Tob Res. .

Abstract

Background: Postmenopausal smokers have difficulty quitting smoking and experience considerable weight gain with smoking cessation. We examined whether adjunctive smoking treatment with exercise, compared to a relaxation control condition, could improve cigarette abstinence, decrease cigarettes smoked per day (CPD), and ameliorate changes in body mass index (BMI) in postmenopausal smokers.

Methods: Women (N = 301) signed informed consent and were randomized to treatment at two sites (Universities of Connecticut and Minnesota). We randomized groups of participants to a comprehensive group treatment program that included 12 weeks of varenicline and either a moderate exercise or relaxation component for 6 months. Participants were followed for a year after medication treatment.

Results: Overall, 17.3% of patients reported carbon monoxide-verified continuous abstinence for the 9- to 12-week period, and 11.6% reported prolonged abstinence at 1 year, with no significant differences between treatment conditions. CPD reported at study visits showed significant main effects for time in weeks, for site, and for treatment. The Exercise condition reported smoking fewer CPD over time, and that advantage widened over time. In terms of BMI, significant effects for time in weeks, and for the interaction of Week × Treatment condition, reflected gradually increasing BMI in these women over time, but with the increase in BMI slower in the Exercise condition.

Conclusions: Exercise, compared to relaxation, was associated with a reduced BMI and CPD in postmenopausal women, but did not increase end of treatment or prolonged abstinence. Further research is needed to devise exercise programs that increase smoking cessation rates in postmenopausal women.

Implications: This study adds to the literature on the effectiveness of a moderate exercise intervention compared to a relaxation control condition as an adjunctive treatment for smoking cessation in postmenopausal women. Our exercise program did not increase end of treatment or prolonged abstinence rates in postmenopausal women; however, there was a beneficial effect on smoking reduction and reduced body mass index. Additional research is needed to devise exercise programs that increase smoking cessation rates in postmenopausal women.

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Figures

Figure 1.
Figure 1.
Participant flow throughout the study.
Figure 2.
Figure 2.
Study treatment overview.
Figure 3.
Figure 3.
Secondary outcomes over time. BMI = body mass index.
See this image and copyright information in PMC

References

    1. U.S. Department of Health and Human Services. Bone Health and Osteoporosis: A Report of the Surgeon General. Rockville, MD: Office of the Surgeon General; 2004.
    1. Alberg AJ, Shopland DR, Cummings KM. The 2014 Surgeon General's report: commemorating the 50th anniversary of the 1964 Report of the Advisory Committee to the US Surgeon General and updating the evidence on the health consequences of cigarette smoking. Am J Epidemiol. 2014;179(4):403–412. - PMC - PubMed
    1. Current cigarette smoking among adults—United States 2017. MMWR Morb Mortal Wkly Rep. 2018. www.cdc.gov/tobacco/data_statistics/fact_sheets/adult_data/cig_smoking/i.... Accessed February 21, 2019. - PMC - PubMed
    1. Jordan H, Hidajat M, Payne N, Adams J, White M, Ben-Shlomo Y. What are older smokers' attitudes to quitting and how are they managed in primary care? An analysis of the cross-sectional English Smoking Toolkit Study. BMJ Open. 2017;7(11):e018150. - PMC - PubMed
    1. Centers for Disease Control and Prevention. Quitting smoking among adults--United States, 2001–2010. MMWR Morb Mortal Wkly Rep. 2011;60(44):1513–1519. - PubMed

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