Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Psychosis

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Psychosis

Jordan Calabrese et al.
Free Books & Documents

Excerpt

Psychosis is an amalgamation of psychological symptoms resulting in a loss of contact with reality. The current thinking is that although around 1.5 to 3.5% of people will meet diagnostic criteria for a psychotic disorder, a significantly larger, variable number will experience at least one psychotic symptom in their lifetime. Psychosis is a common feature to many psychiatric, neuropsychiatric, neurologic, neurodevelopmental, and medical conditions. It is the hallmark feature of schizophrenia spectrum and other psychotic disorders, a co-occurring aspect to many mood and substance use disorders, as well as a challenging symptom to many neurologic and medical conditions. Psychosis can result in high levels of distress for patients and loved ones, which is why it has become a primary target of treatment for medical professionals.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Jordan Calabrese declares no relevant financial relationships with ineligible companies.

Disclosure: Yasir Al Khalili declares no relevant financial relationships with ineligible companies.

References

    1. van Os J, Hanssen M, Bijl RV, Vollebergh W. Prevalence of psychotic disorder and community level of psychotic symptoms: an urban-rural comparison. Arch Gen Psychiatry. 2001 Jul;58(7):663-8. - PubMed
    1. Jellinger KA. Cerebral correlates of psychotic syndromes in neurodegenerative diseases. J Cell Mol Med. 2012 May;16(5):995-1012. - PMC - PubMed
    1. Ismail Z, Nguyen MQ, Fischer CE, Schweizer TA, Mulsant BH, Mamo D. Neurobiology of delusions in Alzheimer's disease. Curr Psychiatry Rep. 2011 Jun;13(3):211-8. - PubMed
    1. Sultzer DL, Leskin LP, Melrose RJ, Harwood DG, Narvaez TA, Ando TK, Mandelkern MA. Neurobiology of delusions, memory, and insight in Alzheimer disease. Am J Geriatr Psychiatry. 2014 Nov;22(11):1346-55. - PMC - PubMed
    1. Fiorentini A, Volonteri LS, Dragogna F, Rovera C, Maffini M, Mauri MC, Altamura CA. Substance-induced psychoses: a critical review of the literature. Curr Drug Abuse Rev. 2011 Dec;4(4):228-40. - PubMed

Publication types

LinkOut - more resources