Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Sep;38(3):148-155.

Pancreatic Cancer Incidence, Mortality, and Survival in Puerto Rico, 2001-2015

M Castañeda-Avila  1 , C R Torres-Cintrón  2 , A Cruz-Benítez  1 , W Fuentes-Payán  1 , A Maldonado-Albertorio  1 , L Nieves-Ferrer  1 , P Padró-Juarbe  1 , R Soto-Abreu  1 , N Perez-Ríos  3 , K J Ortiz-Ortiz  3 , P Magno  4 , A P Ortiz  3
Affiliations

Pancreatic Cancer Incidence, Mortality, and Survival in Puerto Rico, 2001-2015

M Castañeda-Avila et al. P R Health Sci J. 2019 Sep.

Abstract
in English, Spanish

Objective: To perform an epidemiologic profile of pancreatic cancer (PC) in Puerto Rico (PR) with data gathered from 2001 to 2015.

Methods: Using data from the PR Central Cancer Registry we estimated incidence and mortality rates and trends of PC in PR, and performed survival analyses. We also compared the age-standardized incidence and mortality rates of PC in people in PR with those of Hispanics, non-Hispanic whites, and non Hispanic blacks in the United States (US).

Results: From 2011 to 2015, 7.8 per 100,000 persons were diagnosed with PC in PR; higher rates were observed in men than in women (9.2 vs. 6.7 per 100,000, respectively) and in persons 65 years old and older (42.7 per 100,000 persons). For the same period, 6.7 per 100,000 persons died from PC; men and persons 65 years and older had higher mortality rates. Incidence and mortality trends of PC in PR increased from 2001-2015 (annual percent change [APC] = 3.8% and 1.9%, respectively (p<0.05). Lower risk of being diagnosed with and dying from PC was seen in PR than in members of several racial/ethnic groups in the US. The median survival time for PC cases diagnosed in PR during the period of 2008 to 2012 was 5.3 months.

Conclusion: We observed increasing mortality rates and low survival in PC patients in PR. Research on access and response to treatment is needed to elucidate the reasons for the observed results and have a positive impact on PC burden and survival.

Objetivo:: Elaborar un perfil epidemiológico para cáncer de páncreas (CP) en Puerto Rico (PR) de 2001 al 2015.

Metodología:: Utilizando datos del Registro Central de Cáncer de PR (RCCPR) estimamos las tasas y tendencias de incidencia y mortalidad de CP en PR, y realizamos análisis de sobrevida. Además las tasas de incidencia y mortalidad estandarizadas por edad en PR fueron comparadas con hispanos, blancos no hispanos y negros no hispanos en los Estados Unidos (EU). Tendencias de incidencia y mortalidad de CP fueron estimadas además de análisis de sobrevivencia.

Resultados:: Del 2011–2015, 7.8 por 100,000 personas fueron diagnosticadas con CP. La tasa de incidencia fue mayor en los hombres que en las mujeres (9.2 vs. 6.7 por 100,000, respectivamente), y en personas de 65 años o más (42.7 por 100,000 personas). Para el mismo periodo, 6.7 por 100,000 personas murieron de CP, los hombres y las personas de 65 años o más tuvieron mayores tasas de mortalidad. Las tendencias de incidencia y mortalidad de CP en PR aumentaron del 2001 al 2015 (cambio porcentual anual (APC [por sus siglas en inglés]=3.8% y 1.9%, respectivamente (p<0.05). Los puertorriqueños mostraron menor riesgo de ser diagnosticados y morir por CP en comparación con personas de otros grupos raciales/étnicos en los EU. La mediana de tiempo de sobrevivencia para las personas diagnosticadas con CP en PR durante 2008 al 2012 fue de 5.3 meses.

Conclusiones:: Observamos un aumento en mortalidad y una sobrevida baja de CP en PR. Hace falta investigación adicional sobre acceso y respuesta a tratamiento, para elucidar los resultados observados e impactar positivamente la sobrevivencia del CP en PR.

Keywords: Epidemiology; Incidence; Mortality; Pancreatic cancer; Puerto Rico.

PubMed Disclaimer

Conflict of interest statement

The author/s has/have no conflict/s of interest to disclose.

Figures

Figure 1.
Figure 1.. Age-adjusted incidence rates and annual percent change (APC) for pancreatic cancer by sex: Puerto Rico, 2001–2015
*statistically significant (p<0.05) annual percent change (APC)
Figure 2.
Figure 2.. Age-adjusted mortality rates and annual percent changes (APC) for pancreatic cancer by sex: Puerto Rico, 2001–2015
*statistically significant (p<0.05) annual percent change (APC)
Figure 3.
Figure 3.
1- & 3-year relative survival of pancreatic cancer in Puerto Rico by sex and age (2008–2012)
Figure 4.
Figure 4.
Kaplan–Meier curves comparing percent survival for 3 years by histologic type of pancreatic cancer
Figure 5.
Figure 5.
Kaplan–Meier curves comparing percent survival for 3 years by stage at diagnosis
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018;68:394–424. - PubMed
    1. Rahib L, Smith BD, Aizenberg R, Rosenzweig AB, Fleshman JM, Matrisian LM. Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States. Cancer Res 2014;74:2913–2921. - PubMed
    1. SEER Cancer Stat Facts: Pancreatic Cancer. National Cancer Institute. Bethesda, MD. Available at: Url: https://seer.cancer.gov/statfacts/html/pancreas.html. Accessed September 17, 2018.
    1. Lowenfels AB, Maisonneuve P. Epidemiology and Prevention of Pancreatic Cancer. Jpn J Clin Oncol 2004;34:238–244. - PubMed
    1. Torres-Cintrón CR, Alvarado-Ortiz M, Román-Ruiz Y, Ortiz-Ortiz KJ, Zavala-Zegarra D, Tortolero-Luna G. Cancer in Puerto Rico, 2010–2014. Puerto Rico Central Cancer Registry. San Juan, PR. 2017.

Publication types