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Case Reports
. 2019 Sep 18;12(9):e227667.
doi: 10.1136/bcr-2018-227667.

Recovery of second trimester pre-eclampsia after fetal reduction of a triplet

Affiliations
Case Reports

Recovery of second trimester pre-eclampsia after fetal reduction of a triplet

Jeske M Bij de Weg et al. BMJ Case Rep. .

Abstract

Women with a multiple pregnancy are at increased risk of developing hypertensive disorders of pregnancy. We describe a case of a dichorionic triamniotic triplet pregnancy complicated by severe hypertension, proteinuria and maternal symptoms, fitting with the diagnosis of pre-eclampsia, apart from the early gestational age of only 16 weeks. After reduction of the monochorionic pair, the disease resolved and pre-eclampsia was diagnosed again at 30 weeks of gestation, resulting in a delivery on maternal indication at 33 weeks of gestation. In a review of the literature, we found six papers including eight cases on multifetal pregnancy reduction on maternal indication. Multifetal pregnancy reduction resulted in a prolongation of pregnancy of two to 21 weeks and may be considered in extreme early onset pre-eclampsia in dichorionic multiple pregnancies.

Keywords: Obstetrics And Gynaecology; Pregnancy.

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Conflict of interest statement

Competing interests: None declared.

References

    1. Brosens I, Pijnenborg R, Vercruysse L, et al. . The “Great Obstetrical Syndromes” are associated with disorders of deep placentation. Am J Obstet Gynecol 2011;204:193–201. 10.1016/j.ajog.2010.08.009 - DOI - PMC - PubMed
    1. van de Mheen L, Everwijn SM, Knapen MF, et al. . The effectiveness of multifetal pregnancy reduction in trichorionic triplet gestation. Am J Obstet Gynecol 2014;211:536.e1–536.e6. 10.1016/j.ajog.2014.04.023 - DOI - PubMed
    1. van de Mheen L, Everwijn SMP, Haak MC, et al. . Outcome of multifetal pregnancy reduction in women with a dichorionic triamniotic triplet pregnancy to a singleton pregnancy: A retrospective nationwide cohort study. Fetal Diagn Ther 2016;40:94–9. 10.1159/000441650 - DOI - PubMed
    1. Okyay E, Altunyurt S, Soysal D, et al. . A comparative study of obstetric outcomes in electively or spontaneously reduced triplet pregnancies. Arch Gynecol Obstet 2014;290:177–84. 10.1007/s00404-014-3175-y - DOI - PubMed
    1. Hagay ZJ, Levy R, Zalel Y, et al. . Single fetal demise in twin gestation resulting in the resolution of severe pre-eclampsia. Eur J Obstet Gynecol Reprod Biol 1994;56:137–8. 10.1016/0028-2243(94)90271-2 - DOI - PubMed

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