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Review
. 2019 Oct;30(1):4-10.
doi: 10.1177/0022034519872480.

Oral Health Effects of Combusted and Smokeless Tobacco Products

S L Tomar  1 , S S Hecht  2 , I Jaspers  3 , R L Gregory  4 , I Stepanov  2
Affiliations
Review

Oral Health Effects of Combusted and Smokeless Tobacco Products

S L Tomar et al. Adv Dent Res. 2019 Oct.

Abstract

The oral cavity is usually the first part of a consumer's body exposed to the constituents of tobacco products or their emissions. Consequently, the oral cavity is a frequent site for carcinogenic, microbial, immunologic, and clinical effects of tobacco use. This article summarizes 5 presentations on various aspects of oral health affected by combusted or noncombusted tobacco products from a recent conference, "Oral Health Effects of Tobacco Products: Science and Regulatory Policy," sponsored by the American Association for Dental Research and the Food and Drug Administration.

Keywords: Streptococcus mutans; carcinogenesis; electronic nicotine delivery systems; mucosal immunity; nicotine; smoking.

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Conflict of interest statement

The authors declare no potential conflicts of interest with respect to the authorship and/or publication of this article.

Figures

Figure 1.
Figure 1.
Accepted overall mechanism by which cigarette smoking causes cancer.
Figure 2.
Figure 2.
Comparison of aerobic and anaerobic incubation on nicotine-treated Streptococcus mutans biofilm formation. A crystal violet biofilm staining assay (Huang and Gregory 2012) was used to measure the mass of the S. mutans biofilm incubated with different concentrations of nicotine in 96-well microtiter plates. The plates were incubated at 37°C anaerobically or aerobically in 5% CO2. An “a” above the bar indicates a significant difference between the nicotine sample and the 0 nicotine control. A “b” indicates a significant difference between the aerobic and anaerobic samples for that particular nicotine concentration. An “ab” indicates significance for both comparisons. Values are presented as mean absorbance (490 nm) ± SEM
See this image and copyright information in PMC

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