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. 1988:181-7.

Cadaveric renal transplantation at the University of Pittsburgh: a two and one-half-year experience with the point system

R Shapiro  1 , A G Tzakis, T R Hakala, W Lopatin, S Mitchell, B Koneru, A Stieber, R D Gordon, T E Starzl
Affiliations

Cadaveric renal transplantation at the University of Pittsburgh: a two and one-half-year experience with the point system

R Shapiro et al. Clin Transpl. 1988.

Abstract

From January 1, 1986 to July 30, 1988, 530 consecutive cadaver kidney transplantations were performed with patient selection by a point system that took into account time awaiting an organ, donor-recipient matching, degree of presensitization, and some less important factors. The effect of the system was to diminish judgmental factors in case selection which in the past, had probably operated to the disadvantage of "undesirable" potential recipients, including older ones. Primary 1-year graft survival (74%) and graft survival after retransplantation (71%) were lower than in the earlier time. However, the results with triple-drug therapy using CsA, AZA and P demonstrated 88% 1-year graft survival for primary graft recipients and 74% in highly sensitized patients, with comparable patient mortality. These latter observations provide some assurance that the concepts of equitable access and efficient utilization of a scarce resource are not mutually exclusive.

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Figures

Figure 1
Figure 1
Patient and graft survival for 1986–1987.
Figure 2
Figure 2
Pediatric and adult graft survival for 1986–1987.
Figure 3
Figure 3
Primary and retransplant graft survival for 1986–1987.
Figure 4
Figure 4
Graft survival for PRA less than and greater than 40%.
Figure 5
Figure 5
Graft survival for two- and three-drug immunosuppression.
Figure 6
Figure 6
Pediatric and adult graft survival with two- and three-drug immunosuppression.
Figure 7
Figure 7
Primary and retransplant graft survival with two- and three-drug immunosuppression.
Figure 8
Figure 8
Graft survival for PRA less than and greater than 40% with two- and three-drug immunosuppression.
See this image and copyright information in PMC

References

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