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. 2019 Dec 1;34(6):694-698.
doi: 10.21470/1678-9741-2018-0343.

Association of Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratios with In-Hospital Mortality in Patients with Type A Acute Aortic Dissection

Cihan Bedel  1 , Fatih Selvi  1
Affiliations

Association of Platelet to Lymphocyte and Neutrophil to Lymphocyte Ratios with In-Hospital Mortality in Patients with Type A Acute Aortic Dissection

Cihan Bedel et al. Braz J Cardiovasc Surg. .

Abstract

Objective: To evaluate the relationship between neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) with in-hospital mortality in type A acute aortic dissection (AAD).

Methods: A total of 96 patients who presented to the emergency department between January 2013 and June 2018 with a diagnosis of type A AAD were enrolled in this study. White blood cell count subtypes such as NLR and PLR were calculated at the time of admission. The end point was in-hospital mortality.

Results: Of the 96 type A AAD patients included in this analysis, 17 patients (17.7%) died during hospitalization. NLR and PLR were significantly elevated in patients with type A AAD (P<0.001 and <0.001, respectively). Based on the receiver operating characteristic curve, the best NLR cut-off value to predict in-hospital mortality was 9.74, with 70.6% sensitivity and 76.8% specificity, whereas the best PLR cut-off value was 195.8, with 76.5% sensitivity and 78.1% specificity.

Conclusion: Admission NLR and PLR levels were important risk factors and independently associated with in-hospital mortality of type A AAD patients.

Keywords: Aneurysm, Dissecting; Blood Platelets; Hospital Mortality; Hospitalization; Leukocyte Count; Lymphocytes; Risk Factors.

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Conflict of interest statement

No conflict of interest.

Figures

Fig. 1
Fig. 1
Comparison of neutrophil to lymphocyte ratio (NLR) between survivor and non-survivor patients admitted with type A acute aortic dissection.
Fig. 2
Fig. 2
Comparison of platelet to lymphocyte ratio (PLR) between survivor and non-survivor patients admitted with type A acute aortic dissection.
Fig. 3
Fig. 3
Receiver operating characteristic (ROC) curve of NLR and PLR for predicting in-hospital mortality in patients with type A acute aortic dissection. AUC=area under the curve; NLR=neutrophil to lymphocyte ratio; PLR=platelet to lymphocyte ratio
See this image and copyright information in PMC

Comment in

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