doi: 10.1016/j.cgh.2019.09.017.
Epub 2019 Sep 20.
Association Between a Polymorphism in MBOAT7 and Chronic Kidney Disease in Patients With Biopsy-Confirmed Nonalcoholic Fatty Liver Disease
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- PMID: 31546054
- DOI: 10.1016/j.cgh.2019.09.017
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Association Between a Polymorphism in MBOAT7 and Chronic Kidney Disease in Patients With Biopsy-Confirmed Nonalcoholic Fatty Liver Disease
Clin Gastroenterol Hepatol.
2020 Nov.
Abstract
Nonalcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) share risk factors, and recent meta-analysis confirmed that NAFLD is an independent risk factor for incident CKD.1 Genetic variants associated with NAFLD, such as patatin-like phospholipase domain-containing-3 (PNPLA3) rs7384092 and transmembrane 6 superfamily member 2 (TM6SF2) rs5854292,2 have been reported to be associated with renal function in NAFLD subjects.
Copyright © 2020 AGA Institute. Published by Elsevier Inc. All rights reserved.
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