Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Sep 19;16(18):3502.
doi: 10.3390/ijerph16183502.

Early Autism Screening: A Comprehensive Review

Affiliations
Review

Early Autism Screening: A Comprehensive Review

Fadi Thabtah et al. Int J Environ Res Public Health. .

Abstract

Autistic spectrum disorder (ASD) refers to a neurodevelopmental condition associated with verbal and nonverbal communication, social interactions, and behavioural complications that is becoming increasingly common in many parts of the globe. Identifying individuals on the spectrum has remained a lengthy process for the past few decades due to the fact that some individuals diagnosed with ASD exhibit exceptional skills in areas such as mathematics, arts, and music among others. To improve the accuracy and reliability of autism diagnoses, many scholars have developed pre-diagnosis screening methods to help identify autistic behaviours at an early stage, speed up the clinical diagnosis referral process, and improve the understanding of ASD for the different stakeholders involved, such as parents, caregivers, teachers, and family members. However, the functionality and reliability of those screening tools vary according to different research studies and some have remained questionable. This study evaluates and critically analyses 37 different ASD screening tools in order to identify possible areas that need to be addressed through further development and innovation. More importantly, different criteria associated with existing screening tools, such as accessibility, the fulfilment of Diagnostic and Statistical Manual of Mental Disorders (DSM-5) specifications, comprehensibility among the target audience, performance (specifically sensitivity, specificity, and accuracy), web and mobile availability, and popularity have been investigated.

Keywords: DSM-5; autism spectrum disorder; behaviour science; child psychology; clinical diagnosis; machine learning; public health; screening methods.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Similar articles

Cited by

References

    1. Pennington M., Cullinan D., Southern L. Defining autism: Variability in state education agency definitions of and evaluations for Autism Spectrum Disorders. Autism Res. Treat. 2014:1–8. doi: 10.1155/2014/327271. - DOI - PMC - PubMed
    1. Towle P., Patrick P. Autism Spectrum Disorder Screening Instruments for Very Young Children: A Systematic Review. Hindawi Publishing Corporation; New York, NY, USA: 2016. - PMC - PubMed
    1. Allison C., Auyeung B., Baron-Cohen S. Toward brief “red flags” for autism screening: The short autism spectrum quotient and the short quantitative checklist for autism in toddlers in 1000 cases and 3000 controls [corrected] J. Am. Acad. Child. Adolesc. Psychiatry. 2012;51:202–212. doi: 10.1016/j.jaac.2011.11.003. - DOI - PubMed
    1. Thabtah F. Autism spectrum disorder screening: Machine learning adaptation and DSM-5 fulfilment; Proceedings of the 1st International Conference on Medical and Health Informatics; Taichung City, Taiwan. 20–22 May 2017; pp. 1–6.
    1. Thabtah F. Machine learning in autistic spectrum disorder behavioural research: A review. J. Inf. Health Soc. Care. 2019;43:1–20. - PubMed

MeSH terms