Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Sep 20;55(10):615.
doi: 10.3390/medicina55100615.

Vaginal Health in Menopausal Women

Affiliations
Review

Vaginal Health in Menopausal Women

Stefania Alvisi et al. Medicina (Kaunas). .

Abstract

The aim of this review is to provide an overview of genitourinary health in peri- and postmenopause, particularly of vulvovaginal atrophy (VVA), which is part of genitourinary syndrome (GSM). This condition has a high prevalence among post-menopausal women and negatively affects a woman's quality of life. Epidemiology, signs, symptoms, diagnostic criteria of VVA and target treatments for restoring vaginal health are discussed in light of the most recent literature. Issues related to this condition in menopausal women are under-diagnosed, lack objective diagnostic criteria, and consequently under-treated. Over the years, many treatments have been developed but their long-term effectiveness and safety have yet to be clearly defined. Patients are often dissatisfied and stop treatment, suggesting the need for a more personalized and tailored approach to achieve better compliance and thereby effectiveness. The aim of this paper is to provide an overview of the most recent literature on VVA in order to help the gynecologist in the management of this condition.

Keywords: genitourinary syndrome; menopausal women; vaginal health; vulvovaginal atrophy.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure A1
Figure A1
Possible treatment options for vulvovaginal atrophy.
Figure A2
Figure A2
Flow-chart of the management of vulvovaginal atrophy.

References

    1. Portman D.J., Gass M.L. Vulvovaginal Atrophy Terminology Consensus Conference Panel. Genitourinary syndrome of menopause: New terminology for vulvovaginal atrophy from the International Society for the Study of Women’s Sexual Health and the North American Menopause Society. Climacteric. 2014;17:557–563. doi: 10.3109/13697137.2014.946279. - DOI - PubMed
    1. Gandhi J., Chen A., Dagur G., Suh Y., Smith N., Cali B., Khan S.A. Genitourinary syndrome of menopause: An overview of clinical manifestations, pathophysiology, etiology, evaluation, and management. Am. J. Obstet. Gynecol. 2016;215:704–711. doi: 10.1016/j.ajog.2016.07.045. - DOI - PubMed
    1. Palacios S., Castelo-Branco C., Currie H., Mijatovic V., Nappi R.E., Simon J., Rees M. Update on management of genitourinary syndrome of menopause: A practical guide. Maturitas. 2015;82:308–313. doi: 10.1016/j.maturitas.2015.07.020. - DOI - PubMed
    1. Vesco K.K., Beadle K., Stoneburner A., Bulkley J., Leo M.C., Clark A.L. Clinician knowledge, attitudes, and barriers to management of vulvovaginal atrophy: Variations in primary care and gynecology. Menopause. 2019;26:265–272. doi: 10.1097/GME.0000000000001198. - DOI - PubMed
    1. Nappi R.E., Palacios S., Bruyniks N., Particco M., Panay N. The burden of vulvovaginal atrophy on women’s daily living: Implications on quality of life from a face-to-face real-life survey. Menopause. 2019;26:485–491. doi: 10.1097/GME.0000000000001260. - DOI - PubMed