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. 2019 Sep 12;24(18):3331.
doi: 10.3390/molecules24183331.

Polyphenol Composition and (Bio)Activity of Berberis Species and Wild Strawberry from the Argentinean Patagonia

Melina F Chamorro  1 , Gabriela Reiner  1 , Cristina Theoduloz  2 , Ana Ladio  1 , Guillermo Schmeda-Hirschmann  3 , Sergio Gómez-Alonso  4 , Felipe Jiménez-Aspee  5
Affiliations

Polyphenol Composition and (Bio)Activity of Berberis Species and Wild Strawberry from the Argentinean Patagonia

Melina F Chamorro et al. Molecules. .

Abstract

The Argentinean Patagonia berries Berberis microphylla, Berberis darwinii, and Fragaria chiloensis ssp. chiloensis f. patagonica were investigated for their polyphenol content and composition by means of liquid chromatography coupled to diode array detection and electrospray ionization tandem mass spectrometry. The in vitro antioxidant activity and inhibition of metabolic syndrome-associated enzymes (α-glucosidase, α-amylase, and lipase) of the fruit extracts was assessed. The most complex polyphenol profile was found in the Berberis samples, with 10 anthocyanins, 27 hydroxycinnamic acids, 3 proanthocyanidins, 2 flavan-3-ol, and 22 flavonols. Fragaria presented four anthocyanins, nine ellagitannins, two proanthocyanidin dimers, one flavan-3-ol, and five flavonols. The Berberis samples showed the best antioxidant capacity, while Fragaria displayed better activity against α-glucosidase and lipase. The phenolic content and composition of the Argentinean Patagonia berries was similar to that reported for Chilean samples but with some chemical differences between Eastern (Argentina) and Western (Chile) Patagonia. The data obtained supports the consumption of these berries as sources of beneficial polyphenols.

Keywords: Berberis darwinii; Berberis microphylla; Fragaria chiloensis ssp. chiloensis f. patagonica; HPLC-DAD-ESI-MSn; Patagonia; anthocyanins; antioxidant capacity; phenolic compounds.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Fruits from Argentinean Patagonia berries: (a) Berberis darwinii, (b) Berberis microphylla, and (c) Fragaria chiloensis.
Figure 2
Figure 2
HPLC-DAD chromatogram (520 nm) of the anthocyanins from (a) Berberis microphylla, (b) Berberis darwinii, and (c) Fragaria chiloensis. The numbers correspond to Table 2.
Figure 3
Figure 3
HPLC-DAD chromatogram from Berberis microphylla at (a) 280 nm; (b) 320 nm; and (c) 360 nm. The numbers correspond to Table 3.
Figure 4
Figure 4
HPLC-DAD chromatogram from Berberis darwinii at (a) 280 nm; (b) 320 nm; and (c) 360 nm. The numbers correspond to Table 3.
Figure 5
Figure 5
HPLC-DAD chromatogram from Fragaria chiloensis at (a) 280 nm; (b) 320 nm; and (c) 360 nm. The numbers correspond to Table 3.
Figure 6
Figure 6
Main group of phenolic compounds occurring in Berberis and Fragaria chiloensis.
See this image and copyright information in PMC

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