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Comment
. 2019 Sep 23;29(18):R886-R889.
doi: 10.1016/j.cub.2019.08.010.

Transposition: A CRISPR Way to Get Around

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Transposition: A CRISPR Way to Get Around

Tatiana Dimitriu et al. Curr Biol. .
Free article

Abstract

CRISPR-Cas systems provide sequence-specific immunity against selfish genetic elements in prokaryotes. Now, two studies show that transposon-encoded variants can guide sequence-specific transposition. These findings have important practical implications but also raise questions of why and how this strategy would benefit transposons.

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