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Case Reports
. 2019 Sep 24;12(9):e231231.
doi: 10.1136/bcr-2019-231231.

Rare brown tumour of the mandible secondary to tertiary hyperparathyroidism in a renal transplant recipient

Aurélien M Guéroult  1 , Malcolm Cameron  2
Affiliations
Case Reports

Rare brown tumour of the mandible secondary to tertiary hyperparathyroidism in a renal transplant recipient

Aurélien M Guéroult et al. BMJ Case Rep. .

Abstract

Brown tumours are rare osteolytic lesions that occur secondary to hyperparathyroidism (HPT). In 2% of all cases, the craniofacial bones are affected, most frequently the mandible. HPT is classified according to aetiology into three types, of which tertiary HPT is the rarest. Here we present the case of a 42-year-old man who had received a renal transplant 16 years previously and was referred due to swelling on the right side of his jaw. An orthopantomogram revealed a multilocular radiolucency in the right body of the mandible. The bony lesion was treated by surgical enucleation. After histopathological examination of the lesion, the diagnosis of brown tumour of the mandible secondary to tertiary HPT was reached. The patient's recovery was uneventful and follow-up radiography showed good bone healing.

Keywords: calcium and bone; fluid electrolyte and acid-base disturbances; mouth; oral and maxillofacial surgery; renal transplantation.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
An orthopantomogram (OPG) showing a multilocular lucency within the body of the mandible on the right hand side.
Figure 2
Figure 2
CT image of the mandible without contrast showing an expansile lesion centred on the right body of the mandible and thinning of the cortical bone.
Figure 3
Figure 3
Three-dimensional CT image of the lesion.
Figure 4
Figure 4
Follow-up orthopantomogram (OPG) after 6 months showing good infill of the bone defect on the right side.
See this image and copyright information in PMC

References

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