Can precision medicine help achieve the goal of reducing care when the risks exceed the benefits?

Kathryn A Phillips^{1

2}, Deborah A Marshall³, Allison W Kurian⁴

Affiliations

¹ UCSF Center for Translational & Policy Research on Personalized Medicine (TRANSPERS), Department of Clinical Pharmacy, University of California San Francisco, San Francisco, CA 94143, USA.
² UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143, USA.
³ Department of Community Health Sciences, University of Calgary, Calgary, AB T2N 4Z6, Canada.
⁴ Departments of Medicine & of Health Research & Policy, Stanford University, Palo Alto, CA 94304, USA.

Editorial

Kathryn A Phillips et al. Per Med. 2019 Sep.

. 2019 Sep;16(5):365-367.

doi: 10.2217/pme-2019-0045. Epub 2019 Sep 25.

Kathryn A Phillips^{1

2}, Deborah A Marshall³, Allison W Kurian⁴

¹ UCSF Center for Translational & Policy Research on Personalized Medicine (TRANSPERS), Department of Clinical Pharmacy, University of California San Francisco, San Francisco, CA 94143, USA.
² UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143, USA.
³ Department of Community Health Sciences, University of Calgary, Calgary, AB T2N 4Z6, Canada.
⁴ Departments of Medicine & of Health Research & Policy, Stanford University, Palo Alto, CA 94304, USA.

No abstract available

Keywords: economics; evidence-based medicine; precision medicine; preferences.

References

1. Choosing Wisely (2019). https://www.choosingwisely.org/
1. Phillips KA, Schleifer D, Hagelskamp C. Most Americans Do Not Believe That There Is An Association Between Health Care Prices And Quality Of Care. Health Aff (Millwood) 35(4), 647–653 (2016). - PMC - PubMed
1. O’brien BJ, Gertsen K, Willan AR, Faulkner LA. Is there a kink in consumers’ threshold value for cost-effectiveness in health care? Health Econ 11(2), 175–180 (2002). - PubMed
1. Garfield S, Douglas MP, Macdonald KV, Marshall DA, Phillips KA. Consumer familiarity, perspectives and expected value of personalized medicine with a focus on applications in oncology. Per Med 12(1), 13–22 (2015). - PMC - PubMed
1. Sparano JA, Gray RJ, Makower DF et al. Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer. N Engl J Med 379(2), 111–121 (2018). - PMC - PubMed