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Review
. 2019 Aug;14(4):247-255.
doi: 10.1159/000500999. Epub 2019 Jul 30.

AGO Recommendations for the Diagnosis and Treatment of Patients with Locally Advanced and Metastatic Breast Cancer: Update 2019

Marc Thill  1 , Christian Jackisch  2 , Wolfgang Janni  3 , Volkmar Müller  4 , Ute-Susann Albert  5 , Ingo Bauerfeind  6 , Jens Blohmer  7 , Wilfried Budach  8 , Peter Dall  9 , Ingo Diel  10 , Peter A Fasching  11 , Tanja Fehm  12 , Michael Friedrich  13 , Bernd Gerber  14 , Volker Hanf  15 , Nadia Harbeck  16 , Jens Huober  3 , Cornelia Kolberg-Liedtke  7 , Hans-Heinrich Kreipe  17 , David Krug  18 , Thorsten Kühn  19 , Sherko Kümmel  20 , Sibylle Loibl  21 , Diana Lüftner  22 , Michael Patrick Lux  23 , Nicolai Maass  24 , Volker Möbus  25 , Markus Müller-Schimpfle  26 , Christoph Mundhenke  24 , Ulrike Nitz  27 , Kerstin Rhiem  28 , Achim Rody  29 , Marcus Schmidt  30 , Andreas Schneeweiss  31 , Florian Schütz  32 , Hans-Peter Sinn  33 , Christine Solbach  34 , Erich-Franz Solomayer  35 , Elmar Stickeler  36 , Christoph Thomssen  37 , Michael Untch  38 , Frederik Wenz  39 , Isabell Witzel  4 , Achim Wöckel  39 , Nina Ditsch  16
Affiliations
Review

AGO Recommendations for the Diagnosis and Treatment of Patients with Locally Advanced and Metastatic Breast Cancer: Update 2019

Marc Thill et al. Breast Care (Basel). 2019 Aug.

Abstract

Every year the Breast Committee of the Arbeitsgemeinschaft Gynäkologische Onkologie (German Gynecological Oncology Group, AGO), a group of gynecological oncologists specialized in breast cancer and interdisciplinary members specialized in pathology, radiologic diagnostics, medical oncology, and radiation oncology, prepares and updates evidence-based recommendations for the diagnosis and treatment of patients with early and metastatic breast cancer. Every update is performed according to a documented rule-fixed algorithm, by thoroughly reviewing and scoring the recent publications for their scientific validity and clinical relevance. This current publication presents the 2019 update on the recommendations for metastatic breast cancer.

Keywords: AGO grades of recommendation; Bone health; Early and metastatic breast cancer; Locoregional recurrence; Oxford level of evidence; Therapy.

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Conflict of interest statement

The conflict of interest statements of all authors with conflicts of interest can be found in the supplementary material (see www.karger.com/doi/10.1159/000500999).

Figures

Fig. 1
Fig. 1
Adjuvant bone-targeted therapy for improvement of prognosis.
Fig. 2
Fig. 2
Surgery of chest wall recurrence after mastectomy/axillary recurrence.
Fig. 3
Fig. 3
Endocrine-based treatment options for postmenopausal patients with HER2-negative metastatic breast cancer.
Fig. 4
Fig. 4
Treatment of triple-negative metastatic breast cancer independent of genomic BRCA 1/2 mutation.
See this image and copyright information in PMC

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