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Review
. 2019 Jun 27:33:150.
doi: 10.11604/pamj.2019.33.150.15892. eCollection 2019.

Nasopharyngeal tuberculosis: report of four cases and review of the literature

Youssef Darouassi  1 , Abdelfettah Aljalil  1 , Amine Hanine  1 , Amine Enneouali  1 , Brahim Bouaity  1 , Mohamed Mliha Touati  1 , Haddou Ammar  1
Affiliations
Review

Nasopharyngeal tuberculosis: report of four cases and review of the literature

Youssef Darouassi et al. Pan Afr Med J. .

Abstract

Even if tuberculosis is a major cause of morbidity and mortality, nasopharyngeal location is unusual and extremely rare. We report four new cases observed with short time interval suggesting a trend towards increased frequency. The diagnosis was confirmed by histological analysis after a biopsy. The evolution was favorable after anti tuberculosis chemotherapy. In the light of those observations and a review of the literature, we will discuss different characteristics of this disease and we will highlight the need of a systematic biopsy in order to confirm diagnosis and exclude undifferentiated carcinoma especially in endemic regions for both diseases.

Keywords: Tuberculosis; headache; hearing loss; lymph node; nasal obstruction; nasopharyngeal disease; nasopharyngeal neoplasm; nasopharynx; treatment.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Endoscopique view showing a polypoid nasopharyngeal swelling in the first patient
Figure 2
Figure 2
Computed tomography showing nasopharyngeal swelling in the first patient
Figure 3
Figure 3
Computed tomography showing nasopharyngeal swelling with tissue necrosis in the second patient
Figure 4
Figure 4
Histological section showing nasopharyngeal mucosa, epithelioid granulomas with giant cells and beginning of caseous necrosis
See this image and copyright information in PMC

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