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Editorial
. 2019 Aug 1:6:20.
doi: 10.21037/sci.2019.06.01. eCollection 2019.

SETD7 at the heart of chromatin factor interplay

Dalia Barsyte-Lovejoy  1   2
Affiliations
Editorial

SETD7 at the heart of chromatin factor interplay

Dalia Barsyte-Lovejoy. Stem Cell Investig. .
No abstract available

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Conflict of interest statement

Conflicts of Interest: The author has no conflicts of interest to declare.

Figures

Figure 1
Figure 1
SETD7 regulation of the cardiac lineage differentiation. SETD7 levels increase when ESCs differentiate to MES and further CP and CM. SETD7 localizes to chromatin cardiac lineage regulator regions that are enriched in co-activators (p300, SWI/SNF) and RNAP2 as well as activating chromatin marks. SETD7 structure shown below (PDB accession code 1MT6) is shown with SET domain surface colored in blue and MORN repeat surface in green while SAH in SET domain is colored in red. ESCs, embryonic stem cells; MES, mesodermal progenitors; CP, cardiac progenitors; CM, cardiomyocytes; SWI/SNF, SWItch/Sucrose NonFermentable; RNAP2, RNA polymerase II.
See this image and copyright information in PMC

Comment on

References

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