Very Short Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation in Patients With High Bleeding Risk: Insight From the STOPDAPT-2 Trial

Hirotoshi Watanabe¹, Takenori Domei², Takeshi Morimoto³, Masahiro Natsuaki⁴, Hiroki Shiomi¹, Toshiaki Toyota⁵, Masanobu Ohya⁶, Satoru Suwa⁷, Kensuke Takagi⁸, Mamoru Nanasato⁹, Yoshiki Hata¹⁰, Masahiro Yagi¹¹, Nobuhiro Suematsu¹², Takafumi Yokomatsu¹³, Itaru Takamisawa⁹, Masayuki Doi¹⁴, Toshiyuki Noda¹⁵, Hideki Okayama¹⁶, Yoshitane Seino¹⁷, Tomohisa Tada¹⁸, Hiroki Sakamoto¹⁸, Kiyoshi Hibi¹⁹, Mitsuru Abe²⁰, Kazuya Kawai²¹, Koichi Nakao²², Kenji Ando², Kengo Tanabe²³, Yuji Ikari²⁴, Keiichi Igarashi Hanaoka²⁵, Yoshihiro Morino²⁶, Ken Kozuma²⁷, Kazushige Kadota⁶, Yutaka Furukawa⁵, Yoshihisa Nakagawa²⁸, Takeshi Kimura¹; STOPDAPT-2 Investigators

Affiliations

¹ Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Japan (H.W., H. Shiomi, T.K.).
² Department of Cardiology, Kokura Memorial Hospital, Kitakyusyu, Japan (T.D., K.A.).
³ Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T.M.).
⁴ Department of Cardiovascular Medicine, Saga University, Japan (M.N.).
⁵ Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Japan (T. Toyota, Y.F.).
⁶ Department of Cardiology, Kurashiki Central Hospital, Japan (M.O., K. Kadota).
⁷ Department of Cardiology, Juntendo University Shizuoka Hospital, Izunokuni, Japan (S.S.).
⁸ Department of Cardiology, Ogaki Municipal Hospital, Japan (K. Takagi).
⁹ Department of Cardiology, Sakakibara Heart Institute, Fuchu, Japan (M.N., I.T.).
¹⁰ Department of Cardiology, Minamino Cardiovascular Hospital, Hachioji, Japan (Y.H.).
¹¹ Department of Cardiology, Sendai Cardiovascular Center, Japan (M.Y.).
¹² Department of Cardiology, Saiseikai Fukuoka General Hospital, Japan (N.S.).
¹³ Department of Cardiology, Mitsubishi Kyoto Hospital, Kyoto, Japan (T.Y.).
¹⁴ Department of Cardiology, Kagawa Prefectural Central Hospital, Takamatsu, Japan (M.D.).
¹⁵ Department of Cardiology, Gifu Prefectural General Medical Center, Japan (T.N.).
¹⁶ Department of Cardiology, Ehime Prefectural Central Hospital, Matsuyama, Japan (H.O.).
¹⁷ Department of Cardiology, Hoshi General Hospital, Koriyama, Japan (Y.S.).
¹⁸ Department of Cardiology, Shizuoka General Hospital, Japan (T. Tada, H. Sakamoto).
¹⁹ Division of Cardiology, Yokohama City University Medical Center, Japan (K.H.).
²⁰ Department of Cardiology, National Hospital Organization Kyoto Medical Center, Japan (M.A.).
²¹ Department of Cardiology, Chikamori Hospital, Kochi, Japan (K. Kawai).
²² Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center, Japan (K.N.).
²³ Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K. Tanabe).
²⁴ Department of Cardiology, Tokai University Hospital, Isehara, Japan (Y.I.).
²⁵ Hanaoka Seishu Memorial Cardiovascular Clinic, Sapporo, Japan (K.I.H.).
²⁶ Department of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.).
²⁷ Department of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma).
²⁸ Department of Cardiovascular Medicine, Shiga University of Medical Science, Otsu, Japan (Y.N.).

PMID: 31560216
DOI: 10.1161/CIRCULATIONAHA.119.043613

Very Short Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation in Patients With High Bleeding Risk: Insight From the STOPDAPT-2 Trial

Hirotoshi Watanabe et al. Circulation. 2019.

. 2019 Dec 3;140(23):1957-1959.

doi: 10.1161/CIRCULATIONAHA.119.043613. Epub 2019 Sep 27.

Authors

Affiliations

¹ Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Japan (H.W., H. Shiomi, T.K.).
² Department of Cardiology, Kokura Memorial Hospital, Kitakyusyu, Japan (T.D., K.A.).
³ Department of Clinical Epidemiology, Hyogo College of Medicine, Nishinomiya, Japan (T.M.).
⁴ Department of Cardiovascular Medicine, Saga University, Japan (M.N.).
⁵ Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital, Japan (T. Toyota, Y.F.).
⁶ Department of Cardiology, Kurashiki Central Hospital, Japan (M.O., K. Kadota).
⁷ Department of Cardiology, Juntendo University Shizuoka Hospital, Izunokuni, Japan (S.S.).
⁸ Department of Cardiology, Ogaki Municipal Hospital, Japan (K. Takagi).
⁹ Department of Cardiology, Sakakibara Heart Institute, Fuchu, Japan (M.N., I.T.).
¹⁰ Department of Cardiology, Minamino Cardiovascular Hospital, Hachioji, Japan (Y.H.).
¹¹ Department of Cardiology, Sendai Cardiovascular Center, Japan (M.Y.).
¹² Department of Cardiology, Saiseikai Fukuoka General Hospital, Japan (N.S.).
¹³ Department of Cardiology, Mitsubishi Kyoto Hospital, Kyoto, Japan (T.Y.).
¹⁴ Department of Cardiology, Kagawa Prefectural Central Hospital, Takamatsu, Japan (M.D.).
¹⁵ Department of Cardiology, Gifu Prefectural General Medical Center, Japan (T.N.).
¹⁶ Department of Cardiology, Ehime Prefectural Central Hospital, Matsuyama, Japan (H.O.).
¹⁷ Department of Cardiology, Hoshi General Hospital, Koriyama, Japan (Y.S.).
¹⁸ Department of Cardiology, Shizuoka General Hospital, Japan (T. Tada, H. Sakamoto).
¹⁹ Division of Cardiology, Yokohama City University Medical Center, Japan (K.H.).
²⁰ Department of Cardiology, National Hospital Organization Kyoto Medical Center, Japan (M.A.).
²¹ Department of Cardiology, Chikamori Hospital, Kochi, Japan (K. Kawai).
²² Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center, Japan (K.N.).
²³ Division of Cardiology, Mitsui Memorial Hospital, Tokyo, Japan (K. Tanabe).
²⁴ Department of Cardiology, Tokai University Hospital, Isehara, Japan (Y.I.).
²⁵ Hanaoka Seishu Memorial Cardiovascular Clinic, Sapporo, Japan (K.I.H.).
²⁶ Department of Cardiology, Iwate Medical University Hospital, Morioka, Japan (Y.M.).
²⁷ Department of Cardiology, Teikyo University Hospital, Tokyo, Japan (K. Kozuma).
²⁸ Department of Cardiovascular Medicine, Shiga University of Medical Science, Otsu, Japan (Y.N.).

PMID: 31560216
DOI: 10.1161/CIRCULATIONAHA.119.043613

No abstract available

Keywords: hemorrhage; percutaneous coronary intervention; platelet aggregation inhibitors; stents; thrombosis.

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Very Short Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation in Patients With High Bleeding Risk: Insight From the STOPDAPT-2 Trial

Affiliations

Very Short Dual Antiplatelet Therapy After Drug-Eluting Stent Implantation in Patients With High Bleeding Risk: Insight From the STOPDAPT-2 Trial

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LinkOut - more resources

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Medical