Does maternal IgG protect infants from allergen-specific IgE sensitization?

Affiliations

¹ Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: r.aalberse@sanquin.nl.
² Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, The Netherlands.
³ Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

Comment

Rob C Aalberse et al. J Allergy Clin Immunol. 2019 Nov.

. 2019 Nov;144(5):1454-1455.

doi: 10.1016/j.jaci.2019.08.011. Epub 2019 Sep 25.

¹ Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: r.aalberse@sanquin.nl.
² Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, The Netherlands.
³ Department of Immunopathology, Sanquin Research, Amsterdam, The Netherlands; Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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Flicker S, Khaitov M, Valenta R. Flicker S, et al. J Allergy Clin Immunol. 2019 Nov;144(5):1455-1456. doi: 10.1016/j.jaci.2019.08.012. Epub 2019 Sep 25. J Allergy Clin Immunol. 2019. PMID: 31563342 No abstract available.

Maternal allergen-specific IgG might protect the child against allergic sensitization.
Lupinek C, Hochwallner H, Johansson C, Mie A, Rigler E, Scheynius A, Alm J, Valenta R. Lupinek C, et al. J Allergy Clin Immunol. 2019 Aug;144(2):536-548. doi: 10.1016/j.jaci.2018.11.051. Epub 2019 Jan 25. J Allergy Clin Immunol. 2019. PMID: 30685457 Free PMC article. Clinical Trial.