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. 2019 Sep 6:15:2579-2586.
doi: 10.2147/NDT.S203486. eCollection 2019.

Repetitive transcranial magnetic stimulation significantly influences the eating behavior in depressive patients

Katarína Jaššová  1 , Jakub Albrecht  1 , Silvie Čerešňáková  1 , Hana Papežová  1 , Martin Anders  1
Affiliations

Repetitive transcranial magnetic stimulation significantly influences the eating behavior in depressive patients

Katarína Jaššová et al. Neuropsychiatr Dis Treat. .

Abstract

Background: Depressive syndrome is one of the most common of psychiatric diseases and is ranked as the largest single contributor to global disability. Depression worsens the treatment outcomes of comorbid conditions and is a predictor of an increased mortality rate. Frequent comorbidities accompanying depressive syndrome are eating disorders (ED). The novel brain stimulation technique termed repetitive transcranial magnetic stimulation (rTMS) has been developed as a clinical tool to treat depression. Simultaneously the effect of rTMS has been studied on ED.

Purpose: The aim of this study was to monitor the correlation between the improvement in depressive symptoms and changes in eating behavior after rTMS treatment, and potential possibility of the utilization of rTMS in the treatment of these frequent comorbid conditions.

Methods: To map the change in eating behavior, this study follows the changes in answers 5 and 7 in the Zung Self-Rating Depression Scale. The patients were treated with high-frequency rTMS focused on the left dorsolateral prefrontal cortex.

Results: We observed a significant change in both questions. At the same time, the change in both questions correlates with a variance in the overall depressive symptoms.

Conclusion: The rTMS treatment of depressive syndrome resulted in significant clinical improvements, including changes in eating behavior.

Keywords: Zung Self-Rating Depression Scale; depressive syndrome; eating behavior; eating disorders; rTMS.

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Conflict of interest statement

Dr. Katarína Jaššová report grants from Charles University in Prague, grants from Ministry of Education Youth and Sports of the Czech Republic, grants from Ministry of Health the Czech Republic, during the conduct of the study. The authors report no other conflicts of interest in this work.

Figures

Figure 1
Figure 1
The scale of affective disorders in the file. Abbreviations: BAD, bipolar affective disorder; DE, depressive episode; OD, organic depressive disorder; RD, recurrent depressive disorder; ADD, mixed anxiety and depressive disorder.
Figure 2
Figure 2
(A) Overall SDS Index after stimulation. (B) Delta SDS Index after stimulation.
Figure 3
Figure 3
The change in questions 5 and 7 for the file without unusually long stimulation.
Figure 4
Figure 4
(A) Correlation between the change in question 5 and delta SDS Index for the file without unusually long stimulation. (B) Correlation between the change in question 7 and delta SDS Index for the file without unusually long stimulation.
Figure 5
Figure 5
Change in questions 5 and 7 in file with unusually long stimulation.
See this image and copyright information in PMC

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