Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Sep;32(3):139-144.
doi: 10.5152/TurkJOrthod.2019.18094. Epub 2019 Sep 1.

The Prevalence of Cleft Lip and Palate Patients: A Single-Center Experience for 17 Years

Hanife Nuray Yılmaz  1 , Elvan Önem Özbilen  2 , Tuğba Üstün  2
Affiliations

The Prevalence of Cleft Lip and Palate Patients: A Single-Center Experience for 17 Years

Hanife Nuray Yılmaz et al. Turk J Orthod. 2019 Sep.

Abstract

Objective: The aim of the present study was to report the prevalence of cleft lip and palate (CLP), isolated cleft palate (CP), isolated cleft lip (CL), and median cleft (MC) applied in Marmara University School of Dentistry, Department of Orthodontics.

Methods: There were 1058 patients who applied to the center between 2000 and 2017. A total of 1026 patients were included in the study. Files, models, and photographs were evaluated. The patients were divided into six groups: unilateral right or left CLP, bilateral CLP, isolated CP, isolated CL, and MC. The prevalence was identified according to cleft type, side, gender, age, and application year.

Results: The most common type was unilateral CLP (44.3%), which was observed more on the left side (28.9%), followed by CP (28.7%). MC had a minimum ratio (0.3%) between cleft types. Males were more prone to have unilateral CLP (right side, 64.6%) and bilateral CLP (64.1%), whereas females were more prone to have CP (59.9%). The greatest number of applications was recorded in 2004, and the patients mostly applied in the neonatal period (64.9%). The ratios of complete cleft cases in all types of clefts were statistically significantly higher.

Conclusion: Unilateral CLP was the most common cleft type and seen more on the left side. While males were affected more by CLP, isolated CP was seen more in females than in males.

Keywords: Cleft lip and palate; prevalence; single center.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: The authors have no conflict of interest to declare.

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Altunhan H, Annagür A, Konak M, Ertuğrul S, Ors R, Koç H. The incidence of congenital anomalies associated with cleft palate/cleft lip and palate in neonates in the Konya region, Turkey. Br J Oral Maxillofac Surg. 2012;50:541–4. doi: 10.1016/j.bjoms.2011.08.001. - DOI - PubMed
    1. Borçbakan C. An analysis of 1000 cases of cleft lip and palate in Turkey. Cleft Palate J. 1969;6:210–2. - PubMed
    1. Cobourne MT. The complex genetics of cleft lip and palate. Eur J Orthod. 2004;26:7–16. doi: 10.1093/ejo/26.1.7. - DOI - PubMed
    1. Tunçbilek G, Özgür F, Balcı S. 1229 Additional malformations and syndromes in 1229 cleft lip and palate patients. Çocuk Sağlığı ve Hast Derg. 2004;47:172–6.
    1. Tomatir AG, Kiray Vural B, Acikbas I, Akdag B. Registries of cases with neural tube defects in Denizli, Turkey, 2004–2010. Genet Mol Res. 2014;13:8537–43. doi: 10.4238/2014.October.20.30. - DOI - PubMed

LinkOut - more resources