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Case Reports
. 2019 Sep 30;12(9):e230206.
doi: 10.1136/bcr-2019-230206.

Antifungals in a case of basidiobolomycosis: role and limitations

Anjum Saeed  1 , Asaad M Assiri  2 , Ishfaq A Bukhari  3 , Rasha Assiri  4
Affiliations
Case Reports

Antifungals in a case of basidiobolomycosis: role and limitations

Anjum Saeed et al. BMJ Case Rep. .

Abstract

A 10-year-old Saudi boy was diagnosed to have basidiobolomycosis after a stormy course of his ailment. Therapy was initiated with intravenous antifungal, voriconazole, which was well tolerated for 6 weeks except for local excoriation at the site of ileostomy. He developed drug-induced hepatitis on oral voriconazole, therefore, switched to oral itraconazole following which he experienced severe chest pain. Alternatively, co-trimoxazole (bactrim) an antibacterial with antifungal activity was prescribed but he had the intolerance to it as well. Unfortunately, posaconazole as an alternative antifungal was not available in our centre. We report here a Saudi boy who developed an intolerance to most common antifungals used clinically 6 weeks after the therapy was initiated.

Keywords: paediatrics; unwanted effects/adverse reactions.

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Conflict of interest statement

Competing interests: None declared.

References

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