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. 2020 Mar;27(3):484-489.
doi: 10.1111/ene.14092. Epub 2019 Oct 19.

Self-reported visual dysfunction in Parkinson disease: the Survey of Health, Ageing and Retirement in Europe

A G Hamedani  1 , A W Willis  1   2   3
Affiliations

Self-reported visual dysfunction in Parkinson disease: the Survey of Health, Ageing and Retirement in Europe

A G Hamedani et al. Eur J Neurol. 2020 Mar.

Abstract

Background and purpose: Visual dysfunction is a non-motor symptom of Parkinson disease (PD), but its prevalence is unknown as population-based data on the epidemiology of visual symptoms in PD are lacking. The objective was to determine the prevalence of visual dysfunction in PD.

Methods: This was a cross-sectional analysis of data from adults ≥50 years old in the Survey of Health, Ageing and Retirement in Europe (SHARE), a multinational population-based health survey of adults living in one of 27 European countries and Israel. PD diagnosis was self-reported. Impairment in overall, distance or near eyesight was defined as a score of 4 or 5 on a 1-5 scale. Adjusted logistic regression was used to determine the association between PD and self-reported vision.

Results: There were 115 240 age-eligible participants in the SHARE study (mean age 64.3 years, 54% female), of whom 1438 (1.25%) reported a diagnosis of PD. In adjusted logistic regression models, PD was associated with increased odds of impaired overall [odds ratio (OR) 2.67, 95% confidence interval (CI) 1.91-3.72], distance (OR 2.55, 95% CI 2.04-3.19) and near (OR 2.07, 95% CI 1.69-2.55) eyesight. Individuals with PD were also less likely to report having an eye examination within the previous 2 years (OR 0.59, 95% CI 0.38-0.92), but this did not remain statistically significant after adjusting for confounders (OR 0.76, 95% CI 0.47-1.24).

Conclusions: Visual dysfunction is significantly more common in PD than in the general adult population. Visual symptoms are a potentially under-recognized and under-treated source of reduced quality of life in PD patients that require further attention and study.

Keywords: Parkinson disease; epidemiology; non-motor symptoms; vision; visual dysfunction.

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References

    1. Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, et al. MDS clinical diagnostic criteria for Parkinson’s disease. Mov Disord. 2015. October;30(12):1591–601. - PubMed
    1. Armstrong RA. Oculo-Visual Dysfunction in Parkinson’s Disease. J Parkinsons Dis. 2015;5(4):715–26. - PMC - PubMed
    1. Ekker MS, Janssen S, Seppi K, Poewe W, de Vries NM, Theelen T, et al. Ocular and visual disorders in Parkinson’s disease: Common but frequently overlooked. Parkinsonism Relat Disord. 2017. July;40:1–10. - PubMed
    1. Biousse V, Skibell BC, Watts RL, Loupe DN, Drews-Botsch C, Newman NJ. Ophthalmologic features of Parkinson’s disease. Neurology. 2004. January 27;62(2):177–80. - PubMed
    1. Crizzle AM, Classen S, Uc EY. Parkinson disease and driving: an evidence-based review. Neurology. 2012. November 13;79(20):2067–74. - PMC - PubMed

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