Comparison of hematologic and biochemical reference values in specific-pathogen-free 1-month-old Yorkshire pigs and Yorkshire-Landrace crossbred pigs
- PMID: 31571729
- PMCID: PMC6753882
Comparison of hematologic and biochemical reference values in specific-pathogen-free 1-month-old Yorkshire pigs and Yorkshire-Landrace crossbred pigs
Abstract
Analysis of hematologic and biochemical values in pigs is an important basis for biomedical research and veterinary clinical diagnosis. Reference values for specific-pathogen-free (SPF) 1-month-old Yorkshire (Y) pigs and Yorkshire-Landrace crossbred (YL) pigs are limited. The present research aimed to describe and compare the reference values for hematologic and biochemical parameters in such pigs. Blood samples were obtained from 90 Y pigs (52 males and 38 females) and 88 YL pigs (55 males and 33 females), all 1 month old and bred in an SPF environment. Among the 16 hematologic and 15 serum biochemical parameters tested, no significant differences between the Y and YL pigs were found except in the concentration of triglyceride (P < 0.05), and heterosis was not observed. Thus, the values determined in this study can be used as basic reference values for 1-month-old Y and YL pigs and will contribute to the use of SPF pigs in biomedical research.
L’analyse des valeurs hématologiques et biochimiques chez les porcs est une base importante pour la recherche biomédicale et le diagnostic clinique vétérinaire. Des valeurs de référence pour des porcs exempts d’agents pathogènes spécifiques (SPF) âgés de 1 mois de race Yorkshire (Y) ou Yorkshire–Landrace croisée (YL) sont limitées. La présente étude visait à décrire et comparer les valeurs de référence pour des paramètres hématologiques et biochimiques chez ces porcs. Des échantillons sanguins furent obtenus de 90 porcs Y (52 mâles et 38 femelles) et 88 porcs YL (55 mâles et 33 femelles), tous âgés de 1 mois et élevés dans un environnement SPF. Parmi les 16 paramètres hématologiques et les 15 paramètres biochimiques sériques testés, aucune différence significative ne fut trouvée entre les porcs Y et YL sauf pour la concentration de triglycérides (P < 0,05), et aucune hétérosis ne fut observée. Ainsi, les valeurs déterminées dans la présente étude peuvent être utilisées comme valeurs de référence de base pour des porcs Y et YL âgés de 1 mois et vont contribuer à l’utilisation de porcs SPF en recherche biomédicale.(Traduit par Docteur Serge Messier).
Copyright and/or publishing rights held by the Canadian Veterinary Medical Association.
Similar articles
-
Hematologic and biochemical reference intervals for 1-month-old specific-pathogen-free Landrace pigs.Vet Clin Pathol. 2021 Mar;50(1):76-80. doi: 10.1111/vcp.12972. Epub 2021 Feb 7. Vet Clin Pathol. 2021. PMID: 33550680
-
Hematologic and serum biochemical reference values in nontransgenic FVB mice.Comp Med. 2000 Feb;50(1):32-5. Comp Med. 2000. PMID: 10987664 No abstract available.
-
Hematologic and biochemical reference intervals for Norwegian crossbreed grower pigs.Vet Clin Pathol. 2010 Jun;39(2):221-6. doi: 10.1111/j.1939-165X.2009.00199.x. Epub 2009 Dec 30. Vet Clin Pathol. 2010. PMID: 20051064
-
Hematologic and blood chemistry data for the gorilla (Gorilla gorilla).Folia Primatol (Basel). 1972;18(3):300-16. doi: 10.1159/000155485. Folia Primatol (Basel). 1972. PMID: 4650701 No abstract available.
-
Some normal biochemical parameters of pigs in Pupua New Guinea.Trop Anim Health Prod. 1976 May;8(2):71-81. doi: 10.1007/BF02383371. Trop Anim Health Prod. 1976. PMID: 936299
Cited by
-
Beneficial Effects of Combined Use of Extracorporeal Membrane Oxygenation and Hypothermic Machine Perfusion in Porcine Donors after Cardiac Death for Liver Transplantation.J Clin Med. 2023 Sep 18;12(18):6031. doi: 10.3390/jcm12186031. J Clin Med. 2023. PMID: 37762971 Free PMC article.
-
Assessment of PRRSV and PCV2 seroprevalence and antigen prevalence in minipigs at laboratory-animal production facilities.J Adv Vet Anim Res. 2024 Dec 28;11(4):1017-1022. doi: 10.5455/javar.2024.k852. eCollection 2024 Dec. J Adv Vet Anim Res. 2024. PMID: 40013282 Free PMC article.
-
siRNA-mediated reduction of a circulating protein in swine using lipid nanoparticles.Mol Ther Methods Clin Dev. 2024 Apr 27;32(2):101258. doi: 10.1016/j.omtm.2024.101258. eCollection 2024 Jun 13. Mol Ther Methods Clin Dev. 2024. PMID: 38779336 Free PMC article.
-
Hematological reference intervals for Danish crossbred Landrace Yorkshire Duroc (LYD) pigs used in biomedical research.Acta Vet Scand. 2025 Feb 24;67(1):11. doi: 10.1186/s13028-025-00798-6. Acta Vet Scand. 2025. PMID: 39994705 Free PMC article.
-
Biochemical and Hematologic Reference Intervals for Anesthetized, Female, Juvenile Yorkshire Swine.J Am Assoc Lab Anim Sci. 2022 Jan 1;61(1):21-30. doi: 10.30802/AALAS-JAALAS-21-000014. Epub 2021 Dec 13. J Am Assoc Lab Anim Sci. 2022. PMID: 34903312 Free PMC article.
References
-
- Aloi M, Tromba L, Nardo GD, et al. Premature subclinical atherosclerosis in pediatric inflammatory bowel disease. J Pediatr. 2012;161:589–594. - PubMed
-
- Cooper DK, Gollackner B, Sachs DH. Will the pig solve the transplantation backlog? Annu Rev Med. 2002;53:133–147. - PubMed
-
- Chapman LE, Folks TM, Salomon DR, Patterson AP, Eggerman TE, Noguchi PD. Xenotransplantation and xenogeneic infections. N Engl J Med. 1995;333:1498–1501. - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources