Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Nov 16;28(8):1171-1180.
doi: 10.1080/09273948.2019.1646773. Epub 2019 Oct 1.

High-Resolution Imaging of Retinal Vasculitis by Flood Illumination Adaptive Optics Ophthalmoscopy: A Follow-up Study

Marie-Hélène Errera  1   2   3 , Marthe Laguarrigue  4 , Florence Rossant  4 , Edouard Koch  1   2 , Céline Chaumette  1   2 , Christine Fardeau  5 , Mark Westcott  6 , José-Alain Sahel  1   2   3 , Bahram Bodaghi  3   5 , Jonathan Benesty  1   2   3 , Michel Paques  1   2   3
Affiliations
Free article

High-Resolution Imaging of Retinal Vasculitis by Flood Illumination Adaptive Optics Ophthalmoscopy: A Follow-up Study

Marie-Hélène Errera et al. Ocul Immunol Inflamm. .
Free article

Abstract

Purpose: To monitor perivascular sheathing during the course of retinal vasculitis by flood illumination adaptive optics ophthalmoscopy (AOO). Methods: Perivenous sheathing and venous diameters were quantitatively analyzed by semi-automatic segmentation of AOO images in 12 eyes of treatment-naive patients with retinal vasculitis. Results: The width of venous sheathing ranged from 45 to 225 µm (mean 101.0 µm ± 54.3). In 10 cases, the underlying vein showed focal narrowing (mean ± SD 14% ± 10). Focal narrowing of arteries was also present in one eye. At presentation, width of sheathing and vessel diameters were not correlated with fluorescein leakage. During follow-up, 5 eyes showed an increase in vein diameter or resolution of narrowing and in 10 eyes a thinning of vascular sheathing was observed (p= .003). Conclusions: Perivenous sheathing may be quantitatively analyzed and monitored by AOO. AOO may therefore contribute to monitor vascular sheathing during posterior uveitis.

Keywords: adaptive optics; posterior uveitis; retina; retinal vasculitis; uveitis.

PubMed Disclaimer