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. 1985 Jan;27(1):135-6.
doi: 10.1128/AAC.27.1.135.

Therapeutic efficacy of teicoplanin in experimental enterococcal endocarditis

P M Sullam, M G Täuber, C J Hackbarth, M A Sande

Therapeutic efficacy of teicoplanin in experimental enterococcal endocarditis

P M Sullam et al. Antimicrob Agents Chemother. 1985 Jan.

Abstract

The antimicrobial activities of teicoplanin and ampicillin, alone and in combination with gentamicin, were compared in experimental Streptococcus faecalis endocarditis. Bacterial titers in vegetations of rabbits treated with teicoplanin were significantly lower than those of untreated controls (P less than 0.01) and were equivalent to titers in ampicillin-treated animals. Gentamicin increased the activities of both drugs to a comparable degree.

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