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. 2020 Nov;18(12):2843-2845.e2.
doi: 10.1016/j.cgh.2019.09.027. Epub 2019 Sep 28.

Performance of Simple Fibrosis Scores in Nonobese Patients With Nonalcoholic Fatty Liver Disease

Charmaine Fu  1 , Janae Wentong Wai  1 , Nik Raihan Nik Mustapha  2 , Marie Irles  3 , Grace Lai-Hung Wong  4 , Sanjiv Mahadeva  5 , Sarah Shili  3 , Anthony Wing-Hung Chan  6 , Wassil Merrouche  3 , Henry Lik-Yuen Chan  4 , Juliette Foucher  3 , Brigitte Le Bail  7 , Vincent Wai-Sun Wong  4 , Wah Kheong Chan  8 , Victor de Lédinghen  9
Affiliations

Performance of Simple Fibrosis Scores in Nonobese Patients With Nonalcoholic Fatty Liver Disease

Charmaine Fu et al. Clin Gastroenterol Hepatol. 2020 Nov.

Abstract

Because only a minority of patients with nonalcoholic fatty liver disease (NAFLD) have advanced fibrosis and would eventually develop liver-related complications, current guidelines recommend initial assessment with noninvasive tests of fibrosis.1-3 Most previous studies focused on overweight and obese patients. Despite a strong association between obesity and NAFLD, 3%-30% of people with relatively normal body mass index (BMI) may still have NAFLD.4,5 Hence, this study aims to evaluate the performance of the common noninvasive tests in non-obese (BMI <25 kg/m2) and obese (BMI ≥25 kg/m2) NAFLD patients.

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